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IRCT20170215032587N5 IRCT 2019-03-12 Ghoum University of Medical Sciences Pregabalin for the treatment of cough Pregabalin for the treatment of subacute and chronic refractory cough 2019-03-21 anticipated 30 Complete https://irct.ir/trial/37884 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients will be assigned to two groups of intervention and control by block randomization. For this purpose blocks of size 4 will be used. Six blocks will include BAAB, ABBA, BABA, BBAA, ABAB, AABB. To hide the random allocation, the numbered dark envelopes will be used, in which the group name is specified in the random sequence generated. Then, according to the order of entering samples, for the first patient the envelope number one is opened and the group will be identified until the end, Blinding description: Participants and outcome assessor does not know the allocation. 2-3 Cough. Intervention 1: Intervention group: pregabalin capsule, oral, 150 mg, every 12 hours for two weeks. Intervention 2: Control group: placebo capsule, oral, every 12 hours for two weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is The data are specific to this study
public Seyed Hasan Adeli
Qom University of Medical Science, Saheli Street, Qom
Qom Iran (Islamic Republic of) 3713649373 +98 25 3285 2720 Adeli@muq.ac.ir Ghoum University of Medical Sciences scientific Seyed Hasan Adeli
Qom University of Medical Science, Saheli street, Qom
Qom Iran (Islamic Republic of) 3713649373 +98 25 3285 2720 Adeli@muq.ac.ir Ghoum University of Medical Sciences Iran (Islamic Republic of) Subacute cough (between 3 and 8 weeks) or chronic cough 18 years no limit Both History of asthma History of chronic bronchitis Pneumonia, pulmonary abscess or pulmonary tuberculosis Smokers R05 Cough Treatment - Drugs Placebo Intervention group: pregabalin capsule, oral, 150 mg, every 12 hours for two weeks Control group: placebo capsule, oral, every 12 hours for two weeks Number of cough attacks per day. Timepoint: 7 and 14 days after intervention. Method of measurement: Patient statement. Number of coughs per attack. Timepoint: 7 and 14 days after intervention. Method of measurement: Patient statement. Ghoum University of Medical Sciences Approved 2019-01-29 Ethics Committee of Qom University of Medical Sciences No. 83, Alley 4, Alley 1.1, Safashahr Street, Qom Qom Ghoum Iran (Islamic Republic of)