IRCT20170609034406N5 IRCT 2020-07-06 Tabriz University of Medical Sciences Efficacy of pralidoxime in the treatment of organophosphorus poisoning Study of the efficacy of pralidoxime in the treatment of organophosphorus poisoning 2020-06-30 anticipated 86 Complete https://irct.ir/trial/37966 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: None, Randomization description: Simple random randomization is performed by creating random numbers between 10 and 90 by the computer. For numbers less than 45 and 45 people enter the control group and for numbers less than 45 people enter the intervention group. It should be noted that all patients will randomly enter the control or intervention group after selecting to enter the study by assigning a random number generated by the computer. 3 Orghanophosphate poisonous patients. Intervention 1: Intervention group: 43 patients selected by simple random, concomitant treatment with atropine (0.5 mg / ml, Daropakhsh Company) (initial dose of 1-6 mg, which will be repeated every 3-5 minutes if necessary. Double the application will be applied) and pralidexime (2% of SERB) (loading dose 30 mg / kg and up to a maximum dose of 2000, then a maintenance dose of 8-10 mg / kg / h to a maximum of 650 mg / h). Intervention 2: Control group: 43 randomly selected patients, only receive atropine (0.5 mg / ml, Darupakhsh Company) with initial dose of 1-6 mg, that will be repeated every 3-5 minutes if necessary. Dose will doubled if no response reported. No - There is not a plan to make this available Justification or reason for not sharing IPD is Threre is no further information