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IRCT20121216011766N5 IRCT 2019-04-21 Rasht University of Medical Sciences Comparison of the effect of bupivacaine injection alone and in association with dexmedetomidine on pain and complications after inguinal hernia surgery TAP Block Comparing the effect of injecting Bupivacaine alone and in association with dexmedetomidine through transversus abdominis plane (TAP) block with ultrasound-guided on pain and complications after inguinal hernia surgery: A randomized controlled clinical trial 2019-03-21 anticipated 66 Complete https://irct.ir/trial/38034 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients eligible for inclusion will be divided into 2 groups using the Blocked Randomization method. One of the nurses of the relevant ward, who is not aware of the implementation of the study will divide the patients into two groups of 33 marked as I and C as the intervention group and control group. Random sequences will be generated using the Random Generator program. Based on the random block method, 15 blocks of four-block and one six-block will be generated for 66 patients. After producing the list, each person will be assigned a dedicated code and will be recognized by this code during the study, Blinding description: Patients eligible for inclusion will be divided into 2 groups of 33 patients marked as I and C (intervention and control group) using the Blocked Randomization method, by One of the nurses of the relevant ward, who is not aware of the implementation of the study. 3 Transversus abdominis plane (TAP) block with ultrasound guidance on pain and complications after inguinal hernia surgery. Intervention 1: Intervention group:20 milliliters of bupivacaine 0.5% with 1 milliliter (100 micrograms) of dexmedmotidine (Precedex brand containing 200 microgram / 2 milliliter of drug, HOSPIRA manufacturer reference of the United States of America). Intervention 2: Control group: 20 milliliter bupivacaine 0.5% plus 1 milliliter normal saline. Yes - There is a plan to make this available What will be shared: The results of the research will be publicly available without mentioning the participants' names in the form of a research paper When: As soon as the article is published, the information will be publicly available in the general format To whom: researchers Conditions: To do research Where to obtain: Contact the relevant journal site or email and contact the responsible author How to obtain: Contact the relevant journal site or email and contact the responsible author Comments:
public Hoseein Khoshrang
Sardar jungel Avenue
Rasht Iran (Islamic Republic of) 4139638459 +98 132238306 hkhoshrang@yahoo.com Rasht University of Medical Sciences scientific Hoseein khoshrang
Sardar jungel Ave
Rasht Iran (Islamic Republic of) 4139638459 +98 132238306 khoshrang@gums.ac.ir Rasht University of Medical Sciences Iran (Islamic Republic of) 18 to 65 years old Body mass index 35-18 kilogram / meter 2 Lack of drug sensitivity No alcohol and drug addiction Type of surgery including restoration without tension with mesh ASA class I,II 18 years 65 years Both Surgery lasts more than 2 hours Need for concurrent surgery during inguinal hernia surgery Need to get opium in recovery room excessive hemorrhage Recurrence of hernia Need for spinal anesthesia R10.2 Pelvic and perineal pain Treatment - Drugs Treatment - Drugs Intervention group:20 milliliters of bupivacaine 0.5% with 1 milliliter (100 micrograms) of dexmedmotidine (Precedex brand containing 200 microgram / 2 milliliter of drug, HOSPIRA manufacturer reference of the United States of America) Control group: 20 milliliter bupivacaine 0.5% plus 1 milliliter normal saline Comparing the effect of injecting Bupivacaine alone and in association with dexmedetomidine through Transversus Abdominis Plane(TAP) Block with ultrasound guidance in pain and complications after inguinal hernia surgery. Timepoint: In the recovery unit (at 0 o'clock) and at 2, 4, 6, 12, 24 hours after surgery, pain intensity will be measured in the two groups with visual analogue scale (VAS). Method of measurement: In this way, people are asked to show their pain intensity on a 10 cm ruler. no pain will be scored as zero and score 10 is for the highest pain. In 24 hours after surgery that patients are hospitalized in ward , they will be prescribed 0.5 milligram/kilogram of pethidine, if they need painkillers and they state VAS> 3. Also, complications such as nausea, dizziness and vomiting, the first dose and the mean dose of pethidine consumed in the two groups will be investigated. Timepoint: In the recovery unit (at 0 o'clock) and at 2, 4, 6, 12, 24 hours after surgery. Method of measurement: Nausea, dizziness and vomiting. Rasht University of Medical Sciences Approved 2019-02-23 Ethics Committee of Guilan University of Medical Sciences and Health Services Shahid Beheshti Highway Rasht Guilan Iran (Islamic Republic of)