IRCT20190228042868N1 IRCT 2019-05-25 Shahid Beheshti University of Medical Sciences Investigating Prognosis of Early Feeding with Breast milk-Cells in Premature infants Investigating Prognosis of Early Feeding with Breast milk-Cells in Premature infants 2019-04-21 anticipated 128 Complete https://irct.ir/trial/38230 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: According to statistical method : Block randomization, Blinding description: We urge the mothers of both groups to express their own milk.This action will stimulate and secrete more milk for mothers in the coming days and is recommended. Because the low-birth weight infants can not tolerate feeding in routine therapy, the extracted cells are given to the case group. As time goes on, nutrition will be started for both groups, based on the routine (clinical and special condition). 2 Condition 1: Necrotizing enterocolitis (NEC). Condition 2: Bacterial sepsis of newborn. Condition 3: Retinopathy of prematurity. Condition 4: Bronchopulmonary dysplasia. Intervention 1: In the intervention group, feeding with lactating cells started by separating of the fat and protein layer. these neonate can not tolerate whole breast milk. Intervention 2: Control group: Babies who received routine nursing care and after a few days breastfeeding will be started. Yes - There is a plan to make this available What will be shared: All individual data will be available after the publication of the article, after making the participants identifiable. When: Immediately after publication. To whom: It will be available for all researchers. Conditions: To promote breastfeeding and the importance of the compounds and cells in it. Where to obtain: Requests sent to the author's e-mail or other corresponders will be answered as soon as possible. How to obtain: Simple request sent to the corresponding author's email. Comments: Since one of our goals is promoting breastfeeding, we will do our best to publish our findings.