IRCT20120215009014N268 IRCT 2019-04-11 Hamedan University of Medical Sciences Effect of Helicobacter pylori eradication versus no eradication on disease period and treatment response in children with nephrotic syndrome Effect of Helicobacter pylori eradication versus no eradication on disease period and treatment response in children with nephrotic syndrome: a randomized clinical trial 2019-03-11 anticipated 48 Complete https://irct.ir/trial/38268 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients will be randomly assigned to intervention and control groups using block randomization. For this purpose, we will prepare four sheets of paper, writing on two sheets the name of the intervention and on the other two sheets the name of the control. The paper sheets will be pooled, placed in a container, and randomly drawn one at a time for each patient without replacement until all six sheets are drawn. The four paper sheets will be then placed back into the container, and this action repeated until the sample size is reached. 2 Nephrotic syndrome. Intervention 1: Intervention group: Corticosteroid tablet 60 mg/m2 daily for 2 years plus four-drug treatment for 2 weeks with omeprazole capsule 1 mg/kg daily and metronidazole tablet 20 mg/kg daily and ampicillin capsule 50 mg/kg daily and bismuth citrate tablet 480 mg/kg daily for. Intervention 2: Control group: Corticosteroid tablet 60 mg/m2 daily for 2 years. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It depends on the situations and the results of the study as well as approval of the financial supporting organization.