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IRCT20180723040570N2 IRCT 2019-08-14 Iran University of Medical Sciences Comparison of the Effect of Ketamine Infusion with Dexmedetomidine Infusion during Postoperative Fusion of Lumbar Vertigo in Acute Post-Operative Pain. Comparison of the Effect of Ketamine Infusion with Dexmedetomidine Infusion during Postoperative Fusion of Lumbar Vertigo in Acute Post-Operative Pain. 2019-08-05 anticipated 87 Complete https://irct.ir/trial/38335 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: At first, an anesthetist examines patients and then evaluates patients on entry and exit criteria and, if they are satisfied, enter the study. Patients were randomly divided into 3 groups: ketamine (29 patients), doxedmodyntidine (29), and control group (29), Blinding description: The placement of the three groups at the start of the study will be randomized; the selected patients will be divided into three groups: ketamine, dexmedmotidine and control group. The blind is such that the only researcher knows the division of the three groups, and the participant is careful of the analyst assessor and the safety and monitoring committee is completely unaware. 2-3 Posterior fusion surgery of the lumbar spine. Intervention 1: Intervention group1: ketamin Infusion is administered as an infusion at a dose of 0.1 mg / kg per hour.The consumable ketamines are all manufactured by Rotex Germany.As mentioned, the method of administration of the drug is infusion and the duration of administration from the beginning to the end of surgery. Intervention 2: Intervention group2: dexmedetomidine Infusion is administered as an infusion at a dose of 0.2 mg / kg per hour.Consumer dexmedetomidines are all manufactured by Exir Iran and manufactured in Boroujerd factory.As mentioned, the method of administration of the drug is infusion and the duration of administration from the beginning to the end of surgery. Intervention 3: Control group:This group of patients does not receive any analgesic during surgery. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is "No more information".
public Nasim Nikoubakht
No.24,kashfian ave.,sheykhbahayy ave.,molasadra ave.,tehran town
Tehran Iran (Islamic Republic of) 1445613131 +98 21 8862 9854 nikoobakht.n@iums.ac.ir Iran University of Medical Sciences scientific Nasim Nikoubakht
No.24,kashfian ave.,sheykhbahayy ave.,molasadra ave.,tehran town
Tehran Iran (Islamic Republic of) 1445613131 +98 21 8862 9854 nikoobakht.n@iums.ac.ir Iran University of Medical Sciences Iran (Islamic Republic of) Entry criteria included candidates for PSF surgery and ASA1 or ASA2 no limit no limit Both history of the disease Psychiatry systemic diseases such as heart failure, liver, kidney, lung infectious disorder conciousness abnormalities addicted patients G54 Nerve root and plexus disorders Treatment - Drugs Treatment - Drugs Placebo Intervention group1: ketamin Infusion is administered as an infusion at a dose of 0.1 mg / kg per hour.The consumable ketamines are all manufactured by Rotex Germany.As mentioned, the method of administration of the drug is infusion and the duration of administration from the beginning to the end of surgery. Intervention group2: dexmedetomidine Infusion is administered as an infusion at a dose of 0.2 mg / kg per hour.Consumer dexmedetomidines are all manufactured by Exir Iran and manufactured in Boroujerd factory.As mentioned, the method of administration of the drug is infusion and the duration of administration from the beginning to the end of surgery. Control group:This group of patients does not receive any analgesic during surgery. Acute pain after surgery. Timepoint: Enter your recovery & 2&4&6&12 after surjery. Method of measurement: pain ruler. Iran University of Medical Sciences Approved 2018-10-26 Ethics Committee of Iran University of Medical Sciences Amirabad Tehran Tehran Iran (Islamic Republic of)