IRCT20170513033941N52 IRCT 2019-03-28 Arak University of Medical Sciences The effect of Q10 supplementation in treatment of women with polycystic ovary syndrome The effect of Q10 supplementation on metabolic profiles and gene expression related to insulin and lipid in women with polycystic ovary syndrome candidates for IVF 2018-12-17 anticipated 40 Complete https://irct.ir/trial/38393 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: To decrease potential confounding effects, all participants will have stratified randomization according to BMI (<25 and ≥25 kg/m2) and age (<30 and ≥30 y). Then, participants in each block will be randomly allocated into two treatment groups to take either supplements or placebo. Randomization will be done by the use of computer software, Blinding description: Randomization and allocation will be concealed from the researchers and participants until the final analyses are completed. Another person at the Shabihkhani clinic, who is not involved in the trial and not aware of random sequences, will be assigned the participants to the numbered bottles of capsules. 3 Polycystic ovary syndrome. Intervention 1: Intervention group: 100 mg Q10 (Pharmed-Tnt Inc, Canada), once a day, for 8 weeks orally. Intervention 2: Control group: Placebo (Barij Essence, Kashan, Iran), once a day, for 8 weeks orally. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available