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IRCT20190306042948N1 IRCT 2019-04-15 Hamedan University of Medical Sciences Stem cell- based therapy in Asherman syndrome Effects of transplantation of bone marrow, adipose, and endometrial stem cells on endometrium structure and fertility in Ashermans syndrom and endometrial atrophy 2019-05-22 anticipated 10 Complete https://irct.ir/trial/38420 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. N/A Condition 1: Asherman Syndrome. Condition 2: Endometrial Atrophy. Intervention group: Single Stem cells transplanted cell (10000000 cells). Yes - There is a plan to make this available What will be shared: After the completion of the study, information on the main results will be shared. When: After the online publication of the results in the authoritative journal To whom: Researchers and investors in the private sector Conditions: Further study by researchers, an investigation by investors for potential investment in cell therapy Where to obtain: Dr. Sara Soleimani Asl sr_soleimani@yahoo.com +989144529036 How to obtain: Please send your application to the above-mentioned email address, you will receive requested information for less than one month. Comments:
public Sara Soleimani Asl
Shahid Fahmideh BLV, Faculty of Medicine, Hamadan University of Medical Sciences
Hamadan Iran (Islamic Republic of) 6517865178 +98 81 3838 0572 sr_soleimani@yahoo.com Hamedan University of Medical Sciences scientific Sara Soleimani Asl
Hamadan University of Medical Sciences, Hamadan, Iran
Hamadan Iran (Islamic Republic of) 6517865178 +98 81 3838 0023 s.soleimaniasl@umsha.ac.ir Hamedan University of Medical Sciences Iran (Islamic Republic of) Infertile patients referred to the Fatemieh infertility department of Hamadan University of Medical Sciences who suffer from Asherman syndrome or thin endometrium and did not respond to common treatments such as hormone therapy and surgery. 18 years 40 years Female Patients with cardiovascular, renal disorders Patients with Syphilis, Hepatitis, AIDS Patients with husband infertility factor Endometrial thickness more than 7 mm N97.2 A97.2 Female infertility of uterine origin Female infertility of uterine origin Treatment - Other Intervention group: Single Stem cells transplanted cell (10000000 cells) Endometrial thickness. Timepoint: Before transplantation and every month for one year after cell therapy. Method of measurement: Ultrasonography. Menstruation. Timepoint: Monthly for one year after transplantation. Method of measurement: Number of menstruation days and used pads. Fertility percent. Timepoint: For one year following transplantation. Method of measurement: Routine pregnancy tests. FSH. Timepoint: Before and three months following cell transplantation. Method of measurement: Blood sampling. LH. Timepoint: Before and three months following cell transplantation. Method of measurement: Blood sampling. Endometrial adhesion. Timepoint: Before and three month after cell transplantation. Method of measurement: Ultrasonography. Hamedan University of Medical Sciences Approved 2019-02-22 Ethics Committee of Hamadan University of Medical Sciences Shahid Fahmideh BLV. Hamadan University of Medical Sciences Hamadan Hamadan Iran (Islamic Republic of)