IRCT201312073733N3 IRCT 2014-01-03 Isfahan Cardiovascular Research Institute Investigation the effect of hull-less barley bread on lipid profile, fasting blood sugar and effective factors on vascular endothelial function in hypercholestrolemic patients Investigation the effect of hull-less barley bread on lipid profile, fasting blood sugar and effective factors on vascular endothelial function in hypercholestrolemic patients 2013-01-01 anticipated 60 Complete https://irct.ir/trial/3844 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. N/A Hypercholesterolemic. Intervention 1: All subjects were provided with a hypo caloric diet in the calorie range of 1500- 2000 for 4 weeks. the intervention group received the hypocaloric diet containing an experimental bread rich in beta-glucan from oat bran (at least five servings (150 g) per day based on their needs, each serving of which had 6 gram beta-glucan). Their adherence to diet was checked weekly by a dietitian through a diary log in which the daily amounts of all consumed foods including bread were recorded. They were asked to continue their routine levels of physical activity and not to consume fiber supplements, weight loss drugs, herbals medicines, or laxatives. During the course of the intervention, the participants attended weekly visits with the mentioned resident and nutritionist (who evaluated their daily intake of food items. Intervention 2: All subjects were provided with a hypo caloric diet in the calorie range of 1500- 2000 for 4 weeks. The control group consumed the hypocaloric diet with control bread rich in wheat fiber (at least five servings (150 g) per day based on their needs, with no beta-glucan). Their adherence to diet was checked weekly by a dietitian through a diary log in which the daily amounts of all consumed foods including bread were recorded. They were asked to continue their routine levels of physical activity and not to consume fiber supplements, weight loss drugs, herbals medicines, or laxatives. During the course of the intervention, the participants attended weekly visits with the mentioned resident and nutritionist (who evaluated their daily intake of food items.