]>
IRCT20190324043106N1 IRCT 2022-08-05 Gorgan University of Medical Sciences A Comparative study on the effet of Niacin and Sevelamer on decreasing the phosphorous in dialysis patients referring to dialysis department of 5azar medical education center of gorgan in2019(1398) A Comparative study on the effet of Niacin and Sevelamer on decreasing the phosphorous in dialysis patients referring to dialysis department of 5azar medical education center of gorgan in2019(1398) 2019-06-17 anticipated 76 Complete https://irct.ir/trial/38562 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization method: In order to randomize samples, we use a block method with quadrilateral blocks. In this way, one of the following blocks is first selected by accident (for example, with a dice), and according to the order in which those samples are We assign two groups (A for the group receiving Dariviazin and B for the Solamer recipient group). For example, if block 3 is selected and the first one is assigned to the group receiving the drug, and the second and third samples will be allocated to the solamroup recipient group, the fourth will be assigned to the group receiving the drug. Then for four samples, again, a block will be randomly selected. We will allocate it to it and this process will proceed to the end of the sampling. 2-3 Chronic kidney patients undergoing hemodialysis. Intervention 1: Intervention group: Niacin Receiving Group / The first group of patients treated with niacin with a dose of 500 mg per day (100 mg tablets from Abtin Chemical Company); 300 mg in the morning and 200 mg at night with food. Intervention 2: Intervention group: Renagel Recipient Group/ The second group of patients treated with sevelamer with a dose of 1600 mg (800 mg capsules of Faran Chem Company); 800 mg in the morning and 800 mg at night with food. Yes - There is a plan to make this available What will be shared: The level of variables before and after the study / age of the patient / duration of dialysis and sex are informed When: Start the access period 2 months after printing results To whom: For researchers working in academic and scientific institutions Conditions: request and submission of usage documentation in new studies Where to obtain: Golestan University of Medical Sciences / Gorgan - Hirkan Blvd - Golestan University of Medical Sciences / 01732430310 / pr-5azar@goums.ac.ir How to obtain: The applicant will access within 1 month Comments:
public Amirali Falahat
No 12, Ghodse 6 st, Ghods blvd,Valiasr Street,Valiasr Town
Golestan Iran (Islamic Republic of) 4934172345 +98 3232389 amirali_aaf1992@yahoo.com Gorgan University of Medical Sciences scientific Amirali Falahat
No12. Ghodse blvd.Yas bilding
Gorgan Iran (Islamic Republic of) 4934172345 +98 17 3377 5822 amirali_aaf1992@yahoo.com Gorgan University of Medical Sciences Iran (Islamic Republic of) Aged over 18 Obtaining consent Serum phosphorus higher than 6 mg / d Start the dialysis period for more than 3 months No change in treatment protocols (calcium and vitamin D compounds) and dialysis protocol over the past 2 weeks 18 years no limit Both Patient non-cooperation Inadequate medication compliance Known liver diseases Pregnancy Taking carbamazepine N18 Chronic kidney disease (CKD) Treatment - Drugs Treatment - Drugs Intervention group: Niacin Receiving Group / The first group of patients treated with niacin with a dose of 500 mg per day (100 mg tablets from Abtin Chemical Company); 300 mg in the morning and 200 mg at night with food Intervention group: Renagel Recipient Group/ The second group of patients treated with sevelamer with a dose of 1600 mg (800 mg capsules of Faran Chem Company); 800 mg in the morning and 800 mg at night with food P reduction rate. Timepoint: At the beginning of the study and one month later. Method of measurement: blood sample. Gorgan University of Medical Sciences Approved 2019-06-16 ethics committee of golestan university of medical sciences gorgan -hircan ave .golestan university of medical sciences gorgan Golestan Iran (Islamic Republic of)