IRCT20190413043252N1 IRCT 2019-05-18 Rasht University of Medical Sciences The effect of sulfate magnesium on atrial fibrillation after open heart surgery Investigating the effect of sulfate magnesium tablet on atrial fibrillation after coronary artery bypass grafting in Heshmat Hospital in 2019 2019-05-22 anticipated 70 Complete https://irct.ir/trial/38795 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients will be selected based on inclusion criteria and then classified into two groups receiving magnesium sulfate and control group, using the random block method in quadruple blocks based on the obtained list. To generate random sequences in this clinical trial, http://www.graphpad.com/quickcalcs/index.cfm will be used. 3 Atrial fibrillation and fluttery. Intervention 1: Intervention group: All pre-operative patients will be interviewed and the method will be explained to them and written informed consent will be obtained. In both groups, a blood sample for magnesium serum will be taken first and if it is within the normal range (1/5-2/5 milliequivalents per liter), from 48 hours pre-operation, a 250 milligrams magnesium tablet (manufacturer: 21st century)will be given to intervention group at 6 am. This step is done by a collaborator nurse. After surgery and transfer to the ICU, both groups of patients undergo intensive care and ECG monitoring. The intervention group, in case of staying intubated they will take the tablet through NGT tube and if extubated they will take it orally their next 6 am tablet and it will be continued till the fifth day after surgery. The nurse giving the drug to the patient is not in the care team. Magnesium level of plasma in both groups will be controlled daily and if it was higher than the normal range, the medication will be stopped. All this time, a collaborator anesthetist is aware of receiving the drug by intervention group and will intervene immediately in the event of a complication. Intervention 2: Control group: This group does not receive any drug. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is not decided yet