IRCT201210223773N6 IRCT 2013-03-10 Tehran University of Medical Sciences, Medical Faculty comparison of crystalloid and colloid solutions effect on clot formation time and clot firmness after 10 minutes during the upper or lower limbs surgeries comparison of crystalloid and colloid solutions effect on clot formation time and clot firmness after 10 minutes during the upper or lower limbs surgeries 2012-11-21 anticipated 30 Complete https://irct.ir/trial/3881 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 3 Condition 1: clot firmness after 10 minutes. Condition 2: clot formation time. Intervention 1: The first group will receive only crystalloid solutions. Solutions will be prescribed to the 55 ml / kg. Once before and one hour after administration of the solution, blood samples will be taken from three groups of patients. Using Fibtem inhibitor solution, clot formation time and clot firmness after 10 minutes are measured by Thromboelastometer.Statistical analysis of patient records, prescribing of these solutions will be compared. Intervention 2: Solutions will be prescribed to the 55 ml / kg. Once before and one hour after administration of the solution, blood samples will be taken from three groups of patients. Using Fibtem inhibitor solution, clot formation time and clot firmness after 10 minutes are measured by Thromboelastometer.Statistical analysis of patient records, prescribing of these solutions will be compared. Second group will receive modified gelatin. Intervention 3: third group will receive hydroxyethyl Starch6%. Solutions will be prescribed to the 55 ml / kg. Once before and one hour after administration of the solution, blood samples will be taken from three groups of patients. Using Fibtem inhibitor solution, clot formation time and clot firmness after 10 minutes are measured by Thromboelastometer.Statistical analysis of patient records, prescribing of these solutions will be compared.