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IRCT20190427043387N1 IRCT 2019-06-24 Shiraz University of Medical Sciences MIND diet and cognitive function MIND diet Investigating the effect of MIND diet on cognitive performance and metabolic responses in obese adults along with the control of BDNF Val66Met and COMT Val158Met polymorphisms 2018-10-24 anticipated 22 Complete https://irct.ir/trial/39105 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomized will be done using a random number table method. In this way, using Randomization.com, random numbers and blocks are prepared and the numbers are placed inside the envelope, then each participant chooses an envelope after accepting the terms and it is determined by its contents. Which group will be. 3 Neuronal system function. Intervention 1: Intervention group: Participants in the MIND diet group received instruction in modifying the content of their diet to meet MIND pattern guidelines. This pattern emphasizes natural, plant-based foods, specifically promoting an increase in consumption of berries and green leafy vegetables, with limited intakes of animal based and high saturated fat foods. Intervention 2: Control group: This group is told not to change their eating habits during the course of a three-month period. Also, in order to comply with ethical principles and motivate behavior for joining the study, they will give general advice on choosing healthy foods for this group. At the end of the study, the study regime will also be available for control group. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information
public Golnaz Arjmand
School of nutrition and food sience
Shiraz Iran (Islamic Republic of) 7153675541 +98 71 3725 1001 g.arjmand989@gmail.com Shiraz University of Medical Sciences scientific Golnaz Arjmand
Razi Blvd, school of nutrition and diet therapy
Shiraz Iran (Islamic Republic of) 7153675541 +98 71 3725 1007 g.arjmand989@gmail.com Shiraz University of Medical Sciences Iran (Islamic Republic of) 40-60 years old Obese women (Body Mass Index=30-35 kg/m2) Educated subjects normal cognitive function (Mini Mental State examination of survey ≥ 24) People's participation in study 40 years 60 years Female History of severe untreated medical, neurological, and psychiatric diseases which may interfere with the study intervention. Gastrointestinal problems Participated in weight loss program or used weight loss drug in the last 3 months used of multivitamins and minerals that affect cognitive performance over the last 6 months Treatment - Other Placebo Intervention group: Participants in the MIND diet group received instruction in modifying the content of their diet to meet MIND pattern guidelines. This pattern emphasizes natural, plant-based foods, specifically promoting an increase in consumption of berries and green leafy vegetables, with limited intakes of animal based and high saturated fat foods. Control group: This group is told not to change their eating habits during the course of a three-month period. Also, in order to comply with ethical principles and motivate behavior for joining the study, they will give general advice on choosing healthy foods for this group. At the end of the study, the study regime will also be available for control group. Cognitive performance score. Timepoint: Cognitive performance score at the beginning of the study and after the end of the 3 month study period. Method of measurement: PCAP (Persia paper and pencil cognitive assessment package) questioner. Metabolic responces. Timepoint: The beginning and the end of the 3 month study period. Method of measurement: Biochemical tests. Shiraz University of Medical Sciences Approved 2018-10-26 Ethic committee of Shiraz university of medical science School of nutrition and food sience Shiraz Fars Iran (Islamic Republic of)