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IRCT201707293812N6 IRCT 2017-08-08 Connective Tissue research Center- Tabriz University of Medical Sciences The effect of low dose aspirin on platelet inhibition in patients with rheumatoid arthritis The effect of low dose aspirin on platelet inhibition in patients with rheumatoid arthritis 2017-08-23 anticipated 45 Complete https://irct.ir/trial/3931 interventional Randomization: N/A, Blinding: Single blinded, Placebo: Not used, Assignment: Single, Purpose: Prevention. 1 Condition 1: Rheumatoid arthritis. Condition 2: Rheumatoid arthritis. Prescribing 80 mg of asprin on the patient's group and taking the drug for one week.After the last dose and re sampling, blood samples will be used to measure serum TX levels.
public Amir ghorbanihaghjo
Tabriz University of Medical Sciences
Tabriz Iran (Islamic Republic of) +98 41 3336 4666 ghorbaniamir@hotmail.com Tabriz University of Medical Sciences scientific Mahrzad Hajialilo
Tabriz university of Medical Sciences
Tabriz Iran (Islamic Republic of) Iran +33 364666 hajialilo@gmail.com Tabriz university of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Patients with rheumatoid arthritis who have been diagnosed with EULAR 2010 ACR criteria and have been ill for 6 months Exclusion criteria: Includes recent use of aspirin and anti-coagulant drugs, history of aspirin allergy, renal failure (creatinine above 8.1 mg / dL), thrombotic cytopenia, pregnancy, gastric ulcer and gastrointestinal bleeding. Patients with maternal and metabolic disorders are also among the exclusion criteria. no limit no limit Both M06.9 M06.9 Rheumatoid arthritis, unspecified Rheumatoid arthritis, unspecified Treatment - Drugs Prescribing 80 mg of asprin on the patient's group and taking the drug for one week.After the last dose and re sampling, blood samples will be used to measure serum TX levels Platelet aggregation. Timepoint: One week. Method of measurement: Elisa. TXA2. Timepoint: one weak. Method of measurement: Elisa. TX-A2. Timepoint: One week. Method of measurement: Elisa. abriz University of Medical Sciences, Tabriz, Iran Connective Tissue research Center- Tabriz University of Medical Sciences abriz University of Medical Sciences, Tabriz, Iran Approved 2010-09-23 Tabriz Univesity of Medical Sciences Tabriz Univesity of Medical Sciences Tabriz Iran (Islamic Republic of) Approved 2010-08-20 Tabriz University of Medical Sciences Tabriz University of Medical Sciences- Tabriz- Iran Tabriz Iran (Islamic Republic of)