IRCT20190505043485N1 IRCT 2019-06-01 Boushehr University of Medical Sciences Evaluation of oral zinc therapy in Acne Vulgaris disease Determination of the Effect of Oral zinc therapy on the Treatment of Acne vulgaris in Patients with Grade 2 and 3 Acne vulgaris 2019-05-11 anticipated 100 Complete https://irct.ir/trial/39313 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Other, Purpose: Treatment, Randomization description: Among the patients with Acne Vulgaris referred to the Khalij-e-Fars clinic of Bushehr, who are eligible for inclusion in the study, 100 patients are randomly selected and divided into Intervention and control groups by block method, each group Includes 50 patients.To do this, 50 sealed envelopes are used as envelopes A and 50 sealed envelopes as B envelopes. People who select envelope A fall into the control group and those who choose B envelope fall into the intervention group, Blinding description: Data will be analyzed by a statistician without knowing the type of patient treatment. 3 Acne Vulgaris. Intervention 1: Intervention group: Patients in the intervention group in addition to the routine treatment of Acne Vulgaris (containing 1% topical Clindamycin gel and 1% topical Salicylic Acid gel) will receive Zinc Sulfate tablets 60 mg daily orally as a therapeutic intervention for 3 months. Intervention 2: Control group: Patients in the control group received only routine Acne Vulgaris treatment without any extra work. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It is not decided yet