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IRCT20080901001165N47 IRCT 2020-04-16 Islamic Azad University A comparative study of the therapeutic effect of cetirizine and fexofenadine on the control of skin lesions caused by drugs in the intensive care unit(ICU). Comparative study of the therapeutic effect of citrizine and fexofenadine in the control of medication-induced skin lesions in hospital intensive care unit 2018-12-01 anticipated 60 Complete https://irct.ir/trial/39432 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization is conducted using random number table and considering a 1:1 ratio, Blinding description: The patient groups are divided into two groups and except the researcher, other people involved in the study do not know of the intervention or control group. N/A Drug induced skin eruption. Intervention 1: Intervention group: Fexofenadine tablets 120 mg every 12 hours for 10 days. Intervention 2: Intervention group: Cetirizine 10 mg tablet every 12 hours for 10 days. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information
public Yunes panahi
Mollasadra street
Tehran Iran (Islamic Republic of) 1435916471 +98 21 8248 2503 yunespanahi@sbmu.ac.ir Bagheiat-allah University of Medical Sciences scientific Yunes panahi
Mollasadra street
Tehran Iran (Islamic Republic of) 1435916471 +98 21 8248 2503 yunespanahi@sbmu.ac.ir Bagheiat-allah University of Medical Sciences Iran (Islamic Republic of) Patients stay in ICU for at least 48 hours No history of skin diseases Be on medication, so that people in both groups receive their own treatment appropriate to their illness. 18 years no limit Both The patient is in the ICU for less than 48 hours. Find non-pharmacological skin diseases R21 Rash and other nonspecific skin eruption Treatment - Drugs Treatment - Drugs Intervention group: Fexofenadine tablets 120 mg every 12 hours for 10 days Intervention group: Cetirizine 10 mg tablet every 12 hours for 10 days Type of drug-induced skin lesion. Timepoint: Before intervention, 10 days after intervention. Method of measurement: Questionnaire. The severity of the skin lesions. Timepoint: Before intervention, 10 days after intervention. Method of measurement: questionnaire. The extent of skin lesions. Timepoint: Before intervention, 10 days after intervention. Method of measurement: questionnaire. Side effect of Faxofenadine. Timepoint: Before intervention, after ten days. Method of measurement: Questionnaire. Side effect of cetirizine. Timepoint: Before intervention, after ten days. Method of measurement: Questionnaire. Islamic Azad University Approved 2018-08-28 Ethics Committee of Islamic Azad University / Pharmaceutical Sciences Branch Yasaman alley, Yakhchal steet, Shariati street Tehran Tehran Iran (Islamic Republic of)