]>
IRCT20130812014333N122 IRCT 2019-05-25 Kermanshah University of Medical Sciences Effect of Granisetron on blood pressure drops in cesarean delivery Study of the effect of Granisetron in the prevention of blood pressure drops after spinal anesthesia for cesarean delivery 2019-06-10 anticipated 106 Complete https://irct.ir/trial/39502 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomly Individually by random number table via code receipt, Blinding description: In this study, the participants will be kept blinded to the allocation of study groups, dosage of drug and the drug manufacturer. In this way that participants will be unaware of how the participants will be coded and how much the groups will receive. 2-3 Maternal hypotension. Intervention 1: In intervention group, patients will receive 2 mg of Granisetron 5 minutes before the spinal anesthesia via angiocontose. Then, spinal anesthesia with 15 mg of Bupivacaine will be done with a Spinal 25G needle. Intervention 2: In the control group, patients will receive 2 ml of normal saline 5 minutes before the spinal anesthesia via angiocetate. Then, spinal anesthesia with 15 mg of bupivacaine will be done with a spinal 25G needle. Yes - There is a plan to make this available What will be shared: The main outcomes of the study will be shared. When: 3 months To whom: If requested, results will be made available to other academic researchers Conditions: Collected data is confidential and will not be shared with anyone else Where to obtain: To receive the documentation, email send for update manager How to obtain: In a 15-day period, the documents will be sent e-mail Comments:
public Seyedeh Nastaran Tavakoli Lahijani
Emam Reza Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 nassitl@gmail.com Kermanshah University of Medical Sciences scientific Dr. Parisa Golfam
Emam Reza Hospital, Parastar Boulevard
Kermanshah Iran (Islamic Republic of) 6715847141 +98 83 3427 6306 pgolfam@kums.ac.ir Kermanshah University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Pregnant women aged 15-45 ASA Class 1 who are candidate for elective cesarean delivery under spinal anesthesia 15 years 45 years Female Neurological disorders Spinal abnormalities Liver disease BMI>30 O26.5 Maternal hypotension syndrome Treatment - Drugs Treatment - Drugs In intervention group, patients will receive 2 mg of Granisetron 5 minutes before the spinal anesthesia via angiocontose. Then, spinal anesthesia with 15 mg of Bupivacaine will be done with a Spinal 25G needle. In the control group, patients will receive 2 ml of normal saline 5 minutes before the spinal anesthesia via angiocetate. Then, spinal anesthesia with 15 mg of bupivacaine will be done with a spinal 25G needle. Blood pressure drop. Timepoint: Every 3 minutes to 30 minutes, and then every 10 minutes until the end of the surgery. Method of measurement: Using Holter Monitoring. Kermanshah University of Medical Sciences Approved 2019-05-08 Ethics committee of Kermanshah University of Medical Sciences Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences, Building No.2, Shahid Beheshti Kermanshah Kermanshah Iran (Islamic Republic of)