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IRCT20190609043847N1 IRCT 2019-07-23 Gorgan University of Medical Sciences Prevention of post-cesarean infection Comparison of cefazolin and cefazolin plus azithromycin regimens in prevention of infection in caesarean section in Shahid Sayyad Shirazi hospital , 2017-2019 2017-11-21 anticipated 250 Complete https://irct.ir/trial/40044 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: To randomize the first sample, the azithromycin group receiving cefazolin and the second sample will be assigned to the cefazolin group, and this process will proceed to the end of the sampling. An individual who compares the results of the two groups is unaware of the type of intervention. 2 Condition 1: Infection caused by cesarean delivery. Condition 2: Infection following a procedure. Intervention 1: The first group received cefazolin 2 g in 30 minutes before cutting. Intervention 2: The second group received 2 grams in 30 minutes of cefazolin before cutting + 500 mg of oral Azithromycine. Yes - There is a plan to make this available What will be shared: Information on the main outcome can be shared. When: Get started 9 months after printing results To whom: Results will only be available to researchers at university institutes and students. Conditions: Data usage is not a problem if the source is mentioned. Where to obtain: آدرس پست الکترونیک How to obtain: The request will be sent by email and the email will be sent to the data. Comments:
public Zeinab Jalai
No. 4, Boali Ave, Pasdaran Blve, Gorgan.
Gorgan Iran (Islamic Republic of) 4916673353 +98 981732250621 dr.jalali.z@goums.ac.ir Gorgan University of Medical Sciences scientific Zeinab Jalai
No.4, Boali Ave, Pasdaran Blve, Gorgan
Gorgan Iran (Islamic Republic of) 4916673353 +98 17 3225 0621 dr.jalali.z@goums.ac.ir Gorgan University of Medical Sciences Iran (Islamic Republic of) Female candidates for non-elective cesarean section, gestational age of 28 weeks and more, no history of infection before surgery, no use of any antibiotic within a week, no use of any antibiotic other than the antibiotics studied, no history Allergy to any medication preterm rupture of membranes less than 24 hours. 18 years no limit Female Sensitivity to cefazolin or azithromycin Patient unwillingness Get systemic antibiotic in the last 2 weeks Fever prior to cesarean delivery Preterm rupture of membranes more than 24 hours. Get Immunosuppressive Drugs Diseases such as diabetes and immune deficiency Liver disease Kidney and heart failure or pulmonary edema multiple pregnancy pre-eclampsia urinary tract infection or pneumonia Duration of surgery for more than an hour the insertion of subcutaneous ducts during surgery, Abnormal adhesion of placenta O86.0 T81.4 Infection of obstetric surgical wound Infection following a procedure Prevention Prevention The first group received cefazolin 2 g in 30 minutes before cutting The second group received 2 grams in 30 minutes of cefazolin before cutting + 500 mg of oral Azithromycine The incidence of post-cesarean infection. Timepoint: Infection is recorded two to ten days after admission. Method of measurement: The secretion, erythema, and severe swelling of the site, as well as persistent fever, are checked. Gorgan University of Medical Sciences Approved 2018-02-25 Ethics committee of Golestan University of Medical Sciences No. 4, Boali Ave., Pasdaran Blve, Gorgan Gorgan Golestan Iran (Islamic Republic of)