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IRCT20180601039936N1 IRCT 2019-08-03 Ahvaz University of Medical Sciences effect of clonidine in rhinoplasty The effect of oral administration of Clonidine on pain control in patients after Rinoplasty 2019-07-11 anticipated 40 Complete https://irct.ir/trial/40360 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study the randomization will be done using random numbers table. After consultation with the statistics specialist even numbers will be considered for the intervention group and odd numbers for control group. The researcher stays on one of the numbers then the right direction which predefined to move and the numbers will be registered, Blinding description: Participants and researcher will not be aware of the type of treatment. The first clonidine and placebo pill that contatin startch (same to clonidine in shape and color) will be buyed from drug store. Then the nurse will place the clonidine and pantoprazole in the same pack. Only the nurse will be aware of the type of content inside packs. 3 pain. Intervention 1: Intervention group: they must use the 0.2 mg clonidine pill 60-90 minutes before operation. Intervention 2: Control group: they must use the placebo pill 60-90 minutes before operation. No - There is not a plan to make this available Justification or reason for not sharing IPD is no more information
public Dr Saeed Shirafkan
Floor 6, Iranian building, Eastern pahlavan street
Ahvaz Iran (Islamic Republic of) 6153774579 +98 61 3320 5170 Shirafkan.saeed79@gmail.com Ahvaz University of Medical Sciences scientific Dr Saeed Shirafkan
Floor 6, Iranian building, Eastern pahlavan street
Ahvaz Iran (Islamic Republic of) 6153774579 +98 61 3320 5170 Shirafkan.saeed79@gmail.com Ahvaz University of Medical Sciences Iran (Islamic Republic of) rhinoplasty candidate people without systemic disease people with twenty aged and above people without systemic disease 20 years 35 years Both G89 Pain, not elsewhere classified Treatment - Drugs Placebo Intervention group: they must use the 0.2 mg clonidine pill 60-90 minutes before operation Control group: they must use the placebo pill 60-90 minutes before operation Pain. Timepoint: first 24 hours. Method of measurement: The pain status of patients is measured using the Visual Analog Scale (VAS), and patients are asked to specify a range of 0 to 10 for their pain levels. Blood pressure. Timepoint: in first 24 hours. Method of measurement: blood pressure recorded in intervals. Ecchymosis amount. Timepoint: ecchymosis was recorded in first third and seventh day after operation. Method of measurement: ecchymosis in every anatomical area has one point and grading was from zero to thirteen. Analgesic amount request. Timepoint: in first 24 hours. Method of measurement: analgesic request from patients that was paracetamol (acetaminophen) was recorded. Analgesic time. Timepoint: in first 24 hours. Method of measurement: analgesic period that equal to no analgesic request was recorded. Ecchymosis amount. Timepoint: Ecchymosis was recorded in first third and seventh day after operation. Method of measurement: Ecchymosis in every anatomical area has one point and grading was from zero to thirteen. Ahvaz University of Medical Sciences Approved 2018-07-14 Ethics Committee Of Ahvaz Jundi Shapur University Of Medical Sciences Jundi Shapur University Of Medical Sciences, Golestan Street Ahvaz Khouzestan Iran (Islamic Republic of)