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IRCT20130311012782N33 IRCT 2019-08-17 Esfahan University of Medical Sciences Comparison effect of three different drug combinations on Blood Pressure and Heart rate of patients under Bronchoscopy Comparing the effects of Propofol-Ketamine with Propofol-Remifentanile on blood pressure and heart rate changes in patients candidate for Fibro optic Bronchoscopy 2019-09-22 anticipated 76 Complete https://irct.ir/trial/40387 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: In this study, 86 patients candidate for bronchoscopy were selected and divided into two groups of 38 subjects by Random Allocation software , Blinding description: This study is a double-blind clinical trial. Patients and the investigator are not aware about the type of drug injected. The medications are prepared by one of the operating room personnel in the same and encoded syringes and will be given to researcher for injection. N/A Bronchoscopy. Intervention 1: Intervention group: receive 1ug/kg injectable Remifentanil (Razavi Pharmacational institute) with 0.5 mg/kg ketamin(made by Bremore Company) through intravenous infusion. Intervention 2: Control group: receive combination of remifentanyl + propoful. No - There is not a plan to make this available Justification or reason for not sharing IPD is The data belongs to the government agency.
public Ali Mehrabi
Research deputy, School of Medicine, Hezar Jerib Street
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3792 8081 al.mehrabi@gmail.com Esfahan University of Medical Sciences scientific Seyed Taghi Hashemi
Department of anesthesiology, Alzahra hospital, Soffeh St
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 3668 5555 st_hashemi@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) ASA (American Society of Anesthesiologists) < 4 patients candidate for bronchoscopy 18 years 60 years Both body mass index>35 history of alcohol consumption or addiction history of severe allergy history of psychologic diseases history of epilepsy of seizure patient with unstable status Prevention Prevention Intervention group: receive 1ug/kg injectable Remifentanil (Razavi Pharmacational institute) with 0.5 mg/kg ketamin(made by Bremore Company) through intravenous infusion. Control group: receive combination of remifentanyl + propoful Blood Pressure. Timepoint: every 5 minutes during procedure and recovery. Method of measurement: palsoxymetery. Heart rate. Timepoint: every 5 minutes during procedure and recovery. Method of measurement: palsoxymetery. Esfahan University of Medical Sciences Approved 2017-01-31 Ethics Committee of Isfahan University of Medical Sciences Department of anesthesiology, Alzahra hospital, Soffeh street Isfahan Isfehan Iran (Islamic Republic of)