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IRCT20171030037093N14 IRCT 2019-07-02 Shahre-kord University of Medical Sciences Evaluation of the effect of sodium valproate and Levetiracetam on the prevention of migraine headaches Comparison of the effect of sodium valproate and Levetiracetam on the prevention of migraine headaches 2019-07-23 anticipated 80 Complete https://irct.ir/trial/40480 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Diagnostic, Randomization description: Patients are randomly assigned to one of the two groups by selecting the cards named A and B, Blinding description: The drugs were coded without any tags, and the patient randomly selected one of two drugs by choosing the code, and the name of each individual and the prescription drug code was recorded by the clerk. The patient did not have any type of drug. 2 migraine. Intervention 1: Intervention group: The first group received 500 mg of levetiracetam per day. Intervention 2: Intervention group: The second group received 500 mg/day sodium sulfate. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is I will decide until finishing the study
public Mohammadhosein Saffari
Shariati Blvd., Imam Ali Clinic
Shahrekord Iran (Islamic Republic of) 8816788640 +98 38 3224 2696 Dr.safari@gmail.com Shahre-kord University of Medical Sciences scientific Mohammadhosein Saffari
Shariati Blvd., Imam Ali Clinic
Shahrekord Iran (Islamic Republic of) 8816788640 +98 38 3224 2696 Dr.safari@gmail.com Shahre-kord University of Medical Sciences Iran (Islamic Republic of) Age 18 to 65 years old Migraine headache history for at least 6 months before study based on IHS criteria Moderate to severe headache for less than 6 days with Visual Analogue Scale Natural Signs and Natural Nerve Findings. 18 years 65 years Both Patients with kidney failure, liver disease, heart disease, active stomach ulcer disease or diabetes or abnormal vital symptoms Allergy to valproate and Levetiracetam Pregnant or lactating women Cases of other types of headaches such as sinus headaches Taking nonsteroidal anti-inflammatory drugs within 24 hours or valproate over the past 2 weeks G43 Migraine Treatment - Drugs Treatment - Drugs Intervention group: The first group received 500 mg of levetiracetam per day Intervention group: The second group received 500 mg/day sodium sulfate. Headache severity. Timepoint: Before the start of the study, notes were taken every 30 days. Method of measurement: Based on VAS and doctor. Number of headaches per month. Timepoint: Before the start of the study, notes were taken every 30 days. Method of measurement: MIDAS questionnaire. Shahre-kord University of Medical Sciences Approved 2018-07-22 Ethics Committee of Shahrekord University of Medical Sciences Vice chancellor for research, Building No. 2, University headquarters, Ayatollah Kashani Blvd Shahrekord Chahar-Mahal-va-Bakhtiari Iran (Islamic Republic of)