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IRCT20150412021719N2 IRCT 2019-08-16 Islamic Azad University The effect of exercise training with ingested of l-carnitine on angiogenesis The Effects of L-Carnitine Supplementation during Endurance Training on Some Serum Angiogenesis Indices and Blood Pressure Changes in Obese Young Women 2019-07-23 anticipated 40 Complete https://irct.ir/trial/40816 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Simple random, the chance of all subjects for divided into two groups of supplement and placebo were similar, Blinding description: The participants and researchers in this study will be blind to the use of supplementation or placebo. N/A Obesity. Intervention 1: ّFirst intervention group: The subjects of endurance exercise with l- carnitine group will participate in 8 weeks of endurance training with the ingestion of l- carnitine supplement. Blood samples will take in basal state and after 8 weeks. Intervention 2: second intervention group: The subjects of endurance exercise with placebo group will participate in 8 weeks of endurance training with the ingestion of placebo. Blood samples will take in basal state and after 8 weeks. Intervention 3: Third intervention group: The subjects of l- carnitine group will participate in 8 weeks of ingestion of l- carnitine supplement. Blood samples will take in basal state and after 8 weeks. Intervention 4: Control group: The subjects of control group (There will be no intervention). Blood samples will take in basal state and after 8 weeks. Yes - There is a plan to make this available What will be shared: All relevant data and tests will be published without mentioning the name. When: Data will be available after the publication of the articles. To whom: All researchers can access the data. Conditions: The possibility of using this data to analyze and write an article will not be given to individuals. Where to obtain: By emailing the accountability officer, they can access the documentation. How to obtain: After receiving the email, the file will be sent to the researchers. Comments:
public Maryam Ali- Mohammadi
Islamic Azad University, Pasdaran Blvd, Sanandaj
Sanandaj Iran (Islamic Republic of) 6616935391 +98 87 3328 8661 Maryam.alimohamadi66@yahoo.com Islamic Azad University scientific Kamal Aziz-Beigi
Islamic Azad University, Pasdaran Blvd, Sanandaj
Sanandaj Iran (Islamic Republic of) 6616935391 +98 87 3328 8661 kazizbeigi@gmail.com Islamic Azad University Iran (Islamic Republic of) Participants in the current study must be non-athlete Participants in the current study must be at the age range of 20-30 years Participants in the current study must be woman Participants in the current study must be obese 20 years 30 years Female People who consuming tobacco are not allowed to participate in this study People who taking the drug or nutrition supplement are not allowed to participate in this study People who having a kind of special disease are not allowed to participate in this study E66.0 Obesity due to excess calories Prevention Prevention Prevention N/A ّFirst intervention group: The subjects of endurance exercise with l- carnitine group will participate in 8 weeks of endurance training with the ingestion of l- carnitine supplement. Blood samples will take in basal state and after 8 weeks. second intervention group: The subjects of endurance exercise with placebo group will participate in 8 weeks of endurance training with the ingestion of placebo. Blood samples will take in basal state and after 8 weeks. Third intervention group: The subjects of l- carnitine group will participate in 8 weeks of ingestion of l- carnitine supplement. Blood samples will take in basal state and after 8 weeks. Control group: The subjects of control group (There will be no intervention). Blood samples will take in basal state and after 8 weeks. Endothelial growth factor. Timepoint: Basal state and after 8 week. Method of measurement: Based on nanogram per liter with ELISA method. Nitric oxaide. Timepoint: Basal state and after 8 week. Method of measurement: Based on micromole per liter with ELISA method. Interleukin 6. Timepoint: Basal state and after 8 week. Method of measurement: Based on picogram per milliliter with ELISA method. Endostatin. Timepoint: Basal state and after 8 week. Method of measurement: Based on nanogram per liter with ELISA method. Blood pressure. Timepoint: Basal state and after 8 week. Method of measurement: Based on millimeter mercury with digital blood pressure monitor. Interleukin 4. Timepoint: Basal state and after 8 week. Method of measurement: Based on nanogram per liter with ELISA method. Interleukin 8. Timepoint: Basal state and after 8 week. Method of measurement: Based on nanogram per liter with ELISA method. Islamic Azad University Approved 2019-07-15 Ethics committee of Kurdistan University of Medical Sciences Kurdistan University of Medical Sciences, Pasdaran Street Sananndaj Kurdistan Iran (Islamic Republic of)