]>
IRCT20190714044205N1 IRCT 2020-02-18 Esfahan University of Medical Sciences effect of tranexamic acid in reducing bleeding after coronary bypass surgery : A Study on the Effect of 2g Vancomycin paste with 200mg Tranexamic acid Ampoule Compared to Vancomycin with Distilled Water in Reducing Bleeding Amount After Coronary Bypass Surgery 2019-06-22 anticipated 50 Complete https://irct.ir/trial/40820 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Using random allocation software and simple randomization method, 50 eligible patients were assigned into two groups of 25 (control group (vancomycin + normal saline) and intervention group (vancomycin + tranexamic acid). Random assignment by counseling The project statistic was done and finally the codes produced were given by the surgeon assistant who was responsible for the composition of the drugs. The surgeon and the outcome evaluator after surgery only had access to the codes, Blinding description: After preparation of vancomycin paste made with tranexamic acid or normal saline, the paste was given to the surgeon without any information about the content. Paste was used by the surgeon on the sternum bone and the data were collected by an evaluator without any information about the type of paste. 3 Bleeding after open heart surgery. Intervention 1: Intervention group: In the intervention group, a vancomycin 2g paste with 200 mg tranexamic acid ampoule was applied to the sternum bone. Intervention 2: Control group: Control group received two grams of vancomycin with normal saline. Yes - There is a plan to make this available What will be shared: The first 12 hours after the first 24 hours after the operation, the first 48 hours after the operation When: 1399 To whom: all Conditions: all Where to obtain: 09120643032 How to obtain: After a month Comments:
public Hafez Asadollahi
West Laleh Blvd Kooye Alikhani
Esfahan Iran (Islamic Republic of) 245632455 +98 912 064 3032 hafez.perfusion96@gmail.com Esfahan University of Medical Sciences scientific Amir Mir Mohammad Sadeghi
Chamran Hospital
Esfahan Iran (Islamic Republic of) 74513441225 +98 31302610061 13655631omid@gmail.com Esfahan University of Medical Sciences Iran (Islamic Republic of) selective CABG surgery Patient satisfaction to participate in the study 35 years 80 years Both coagulation disorder receive heparin and other anticoagulants 48 hours before surgery history of renal failure and thrombosis taking antiplatelet drugs within 5 days before surgery Treatment - Drugs Treatment - Drugs Intervention group: In the intervention group, a vancomycin 2g paste with 200 mg tranexamic acid ampoule was applied to the sternum bone. Control group: Control group received two grams of vancomycin with normal saline. Bleeding. Timepoint: 12-24-48 hours after surgery. Method of measurement: Via chest Buttel in icu section. Esfahan University of Medical Sciences Approved 2019-07-13 Ethics Committee of Isfahan University of Medical Sciences West Tulip Blvd Koi Alikhani Mother Apartment esfahan Isfehan Iran (Islamic Republic of)