IRCT20190717044253N1 IRCT 2019-08-28 Qazvin University of Medical Sciences Pentraxin-3 concentration in gingival crevicular fluid Effect of non-surgical periodontal therapy on pentraxin-3 concentration in gingival crevicular fluid of chronic periodontitis patients 2017-09-10 anticipated 50 Complete https://irct.ir/trial/41057 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Diagnostic. N/A Generalized moderate chronic periodontitis. Intervention 1: Control group: receive no treatment. Intervention 2: Participants receive oral hygiene instructions (the rolling method twice a day) .Phase I periodontal therapy is performed for periodontitis patients in two sessions with a one-week interval, and includes scaling and root planing with hand and ultrasonic instruments. No antibiotic or anti-inflammatory agent is prescribed for patients. Periodontitis patients are recalled six weeks after the second treatment session. Gingival crevicular fluid is collected again from the same area and clinical parameters are measured again. All procedures will be performed by the same operator . The patients are recalled two weeks after the second scaling session and their adherence to oral hygiene instructions is evaluated. Supragingival prophylaxis is also performed for them . Gingival crevicular fluid is collected using Periopaper . Paper strip is inserted into the gingival crevice and remained there for one minute. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information exists.