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IRCT20190808044478N1 IRCT 2019-10-20 Allameh Tabataba'i University Effect of cognitive remediation on Schizpohrenia Effect of computer-assisted cognitive remediation on negative symptoms, depression and cognitive functions in Schizophrenic patients 2019-09-29 anticipated 30 Complete https://irct.ir/trial/41576 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Other design features: Research will be conducted in multiple clinical centers, Randomization description: We will use Stata 9.0 computer software for simple randomization. Once the difference between groups in important variables (age, gender, IQ, CDSS score, SANS score, cognitive test scores) is not significant; patients will be assigned to either of intervention or control group, Blinding description: Evaluators who are in charge of doing tests and nurses and other personnel of each clinical center are blinded to Both aim and group allocations. Participants are blinded to the aim of research but are aware of group randomization. Participants are also aware of intervention protocol and the fact that there are two groups in the study, but they are not aware of the aim of study which is enhancing cognitive abilities and improving negative symptoms and depressed mood. N/A Schizophrenia. Intervention 1: Intervention group: Set of cognitive exercises will be delivered to patients via computer. Each session consists of 7 exercises in approximate time of 30-45 minutes, 5 times per week for 3 executive weeks for each patient. Intervention 2: Control group: Patients in this group will get treatment as usual (TAU) and will not get cognitive intervention. Yes - There is a plan to make this available What will be shared: After the data was made anonymous, it will be shared using excel format. When: Data will be available after publishing final results. To whom: Data will be available for scientific use for researchers and universities in the field of psychology and also schizophrenia treatment centers. Conditions: In order to obtain detailed information on the study and using in meta-analytic and systematic review studies. Where to obtain: Farideh Hossein Sabet, Third floor, Psychology and Educational Science faculty, Allameh Tabataba'i University and also alirezajamalu@gmail.com How to obtain: Each request will be responded after 2-7 days. Comments:
public Alireza Jamaloo
Flat 3, No.15, Bahar alley, Habibollah st, Sattarkhan st, Tehran
Tehran Iran (Islamic Republic of) ۱۴۵۵۷۹۴۹۹۱ +98 21 6652 2396 alirezajamalu@gmail.com Allameh Tabataba'i University scientific Alireza Jamaloo
Flat 3, No.15, Bahar alley, Habibollah st, Sattarkhan st, Tehran
Tehran Iran (Islamic Republic of) ۱۴۵۵۷۹۴۹۹۱ +98 21 6652 2396 alirezajamalu@gmail.com Allameh Tabataba'i University Iran (Islamic Republic of) Diagnosed with Schizophrenia Score of 6 (at least) on Calgary Depression Scale for Schizophrenia No history of brain damage No drug or alcohol abuse No impairment in visual or hearing ability Absence of Disorganized symptoms IQ of 70 at least, based of estimation using WSCI Word Inventory subtest 18 years 59 years Both Disabling medical condition Not being consent F20 Schizophrenia Rehabilitation Rehabilitation Intervention group: Set of cognitive exercises will be delivered to patients via computer. Each session consists of 7 exercises in approximate time of 30-45 minutes, 5 times per week for 3 executive weeks for each patient. Control group: Patients in this group will get treatment as usual (TAU) and will not get cognitive intervention. Score on the Calgary Depression Scale for Schizoprenia. Timepoint: A week before intervention, A week after intervention. Method of measurement: Calgary Depression Scale for Schizophrenia. Negative Symptoms. Timepoint: A week before intervention, a week after intervention. Method of measurement: Scale for the Assessment of Negative Symptoms. Cognitive Functions. Timepoint: A week before intervention, a week after intervention. Method of measurement: Using following tests: Trail Making Test, Wisconsin Card Sorting Test, Tower of London, Vocabulary and Digit Span subsets of WAIS, Continuous Performance Test. Allameh Tabataba'i University Approved 2019-07-15 Research Ethics Committee of Allameh Tabataba'i University Dehkadeh Square, Dehkadeh-ye-Olympic, Tehran Tehran Tehran Iran (Islamic Republic of)