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IRCT20190728044360N1 IRCT 2019-12-11 Shahed University Effect of Ferula Assafoetida on polycystic ovarian syndrome Effect of Ferula assafoetida on clinical and paraclinical indices of polycystic ovarian syndrome and its comparison with LD tablet. 2019-12-11 anticipated 30 Complete https://irct.ir/trial/41712 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Method: Simple randomization Unit: Individual Tool: Random numbers table, Blinding description: All participants in this project and the clinical caregiver who is responsible for getting medication to the participants and the physician (researcher) who collects the data, are blind to the type of intervention provided to each participant. 3 Polycystic ovarian syndrome. Intervention 1: Case group: This group will be treated with Ferual Assafoetida (1 gram daily) for three weeks and discontinue the consumption for one week. Thereafter, patients will use the drugs for an extra three weeks. Intervention 2: Control group: This group will be treated with LD tablet with formulation of 0.03 mg Ethinyl Estradiol and 0.3 mg Norgestrel or 0.15 mg Levonorgestrel for three weeks and discontinue the consumption for one week. Thereafter, patients will use the drugs for an extra three weeks. Yes - There is a plan to make this available What will be shared: The information about the main outcome will shared. When: The access period begins 6 months after publishing of results. To whom: It will be accessible to everyone. Conditions: For scientific works with observing the principles of research ethics Where to obtain: Najme Dehparvar, Mobile number: 00989122530421, Email: dehparvar.mah@gmail.com, Address: No. 26, Alley 2, Razavi Boulevard, Jahad Square, Qom How to obtain: Upon confirmation of the scientific identity of the Iranian questioner, he or she will be provided as soon as possible. Comments:
public Najmeh Dehparvar
No. 26, Alley 2, Razavi Boulevard, Jihad Square, Bajak
Qom Iran (Islamic Republic of) 3713663547 +98 25 3770 1938 n.dehparvar@shahed.ac.ir Shahed University scientific Najmeh Dehparvar
No. 26, Alley 2, Razavi Boulevard, Jihad Square, Bajak
Qom Iran (Islamic Republic of) 3713663547 +98 25 3770 1938 dehparvar.1406@yahoo.com Shahed University Iran (Islamic Republic of) All 15 to 40 years old women with polycystic ovarian syndrome 15 years 40 years Female Pregnancy Allergy to Ferula Asafoetida Diabetic patients Thyroid diseases E28.2 Polycystic ovarian syndrome Treatment - Drugs Treatment - Drugs Case group: This group will be treated with Ferual Assafoetida (1 gram daily) for three weeks and discontinue the consumption for one week. Thereafter, patients will use the drugs for an extra three weeks. Control group: This group will be treated with LD tablet with formulation of 0.03 mg Ethinyl Estradiol and 0.3 mg Norgestrel or 0.15 mg Levonorgestrel for three weeks and discontinue the consumption for one week. Thereafter, patients will use the drugs for an extra three weeks. Presence of ovarian cysts. Timepoint: Before Intervention and seven days after Intervention. Method of measurement: Sonography. Occurrence of menstrual bleeding. Timepoint: 4 and 8 weeks after the beginning of treatment. Method of measurement: asking. Hirsutism. Timepoint: Before Intervention and seven days after Intervention. Method of measurement: Ferriman–Gallwey scale. Body mass index. Timepoint: Before Intervention and seven days after Intervention. Method of measurement: Meter and scale. Total Testosterone. Timepoint: Before Intervention and seven days after Intervention. Method of measurement: CLIA laboratory method. Free Testosterone. Timepoint: Before Intervention and seven days after Intervention. Method of measurement: ELIZA laboratory method. Shahed University Approved 2018-12-24 Ethics committee on Biomedical Research of Shahed University Shahed University, Persian Gulf Highway (Tehran - Qom), Tehran Tehran Tehran Iran (Islamic Republic of)