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IRCT20150125020795N6 IRCT 2019-11-09 Vice chancellor for research of Tabriz University of Medical Sciences Effect of Premedication with Methylprednisolon or Dexamethason in Severity of Pain after Infusion of Propofol. Effect of Premedication with Methylprednisolon or Dexamethason in Severity of Pain after Infusion of Propofol. 2019-09-23 anticipated 120 Complete https://irct.ir/trial/41938 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The sampling is done by easy burst method and according to patient referral to operating room. Randomization method is pre and post accidental blocks and will be done by Randlist software, Blinding description: All of Patients do not Know about used Drugs in this Study. Two Anesthesiologist who evaluated clinical response to administerated drugs. N/A Post Injectional Pain of Propofol. Intervention 1: Intervention group: Patients will be injected 125 milligram Methylprednisolon in 5 milliliter total volume with normal saline. Intervention 2: Intervention group: Patients will be injected 0.25 or 0.5 milligram Dexamethasone per kilogram of body weight in 5 milliliter total volume that diluted by normal saline. Intervention 3: Control group: Patients will be injected by 5 milliliter of normal saline. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Samad Eslam Jamal Golzari
Departement of Anesthesiology, Faculty of Medicine, Golgasht Street
Tabriz Iran (Islamic Republic of) 5166614766 +98 41 3334 1994 golzaris@tbzmed.ac.ir Tabriz University of Medical Sciences scientific Samad Eslam Jamal Golzari
Department of Anesthesiology, Faculty of Medicine, Golgasht street
Tabriz Iran (Islamic Republic of) 5166614766 +98 41 3334 1994 golzaris@tbzmed.ac.ir Tabriz University of Medical Sciences Iran (Islamic Republic of) All of Patients who Being a Candidate for Elective Surgery and Based on ASA Classification are 1 or 2 ASA Class 15 years 65 years Both Patients with Cardiovascular, Hepatic and Kidney Disease. Need for Rapid Sequence Induction of Anesthesia. Patients with Psychiatric Disorders. Patients under Prescription of Sedative Drugs in the last 24 hours. T88.59 Other complications of anesthesia Treatment - Other Treatment - Other Placebo Intervention group: Patients will be injected 125 milligram Methylprednisolon in 5 milliliter total volume with normal saline. Intervention group: Patients will be injected 0.25 or 0.5 milligram Dexamethasone per kilogram of body weight in 5 milliliter total volume that diluted by normal saline. Control group: Patients will be injected by 5 milliliter of normal saline. Post injectional pain of propofol. Timepoint: Amount of pain evaluate on 5, 10, 15 and 20 seconds after injection of propofol. Method of measurement: Four Numerical Verbal Rating Scale. Vice chancellor for research of Tabriz University of Medical Sciences Approved 2019-07-03 Ethics committee of Tabriz University of Medical Sciences Faculity of Medicine, Golgasht Street Tabriz East Azarbaijan Iran (Islamic Republic of)