IRCT20190914044767N1 IRCT 2019-12-19 Traditional Medicine & Materia Medica Research center Shahid Beheshti university of Medical Sciences Effect of topical cream ,containing Tragacanth on the Eczema and it’s comparison with Mometasone 0.1% Evaluating the efficacy of topical cream based on Iranian traditional medicine containing Tragacanth, White wax and Bitter almond oil on the symptoms management of Eczema (clinical study) and it’s comparison with Mometasone 0.1% 2019-12-21 anticipated 42 Complete https://irct.ir/trial/42115 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Factorial, Purpose: Treatment, Randomization description: Randomization was performed in a randomized, individualized, block with statistical software. The randomization list is available to the researcher. and given to the participants, according to the order of the herbal cream (intervention group) or the mometasone cream (control group). The herbal cream containers are labeled blue and the mometasone cream containers are labeled red; shown in the randomization list in letters A and B, respectively, Blinding description: The blinding of the study is done in a way that the labels of the medicine containers are labeled by the researcher, and patients are initially told that when you participate in the project, you are randomly given a herbal or chemical cream, so Patient and physician are not aware of consumed content. The data is also shown to the data analyzer by code A and B. 3 Mild to moderate hand eczema. Intervention 1: Control group: The group receiving the cream is Momtazone 0.1% manufactured by Kish Medifarm Company in Iran. The cream is applied for 3 weeks every night and then for 2 weeks every other night until they heal. Intervention 2: Intervention group: The group receiving the cream consists of a tragacanth made by a researcher at the Shahid Beheshti Traditional School of Medicine Laboratory in Iran, applied the cream every night until healing. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Due to the probability of a patent being filed for research, no decision has yet been made to publish it.