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IRCT20100102002954N17 IRCT 2019-09-20 Shahroud University of Medical Sciences A Comparative study of Doxycycline and Zinc Sulfate with Doxycycline in the treatment of acne A Comparative study of Doxycycline and Zinc Sulfate with Doxycycline in the treatment of acne vulgaris patients 2019-10-06 anticipated 140 Complete https://irct.ir/trial/42202 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization was done using permuted block randomization method using blocked random allocation syntax in SPSS software. For calculation sample size, number of blocks and block size was determined. Block size was 4. Allocation concealment was done using closed opaque envelope. 3 Acne vulgaris. Intervention 1: Intervention group:: Using Doxycycline capsula (Pars darou Company) in a double dose (200 mg/day) orally for three months in addition using Zinc sulfat tablet (Alborz company) daily (220mg/day) for three months. Intervention 2: Control group: Using Doxycycline capsula (Pars darou Company) in a double dose (200 mg/day) orally for three months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is After completing the research and summarizing the results, it will be decided.
public Dr.Mohammad Bagher Sohrabi
Imam Hossein Hospital, End Imam street, Shahroud, Iran.
Shahroud Iran (Islamic Republic of) 3616611151 +98 23 3234 2000 mb.sohrabi@shmu.ac.ir Shahroud University of Medical Sciences scientific Dr. Marjan Talebi
Imam Hossein hospital., End Imam street., Shahroud., Iran
Shahroud Iran (Islamic Republic of) 3616611151 +98 23 3234 2000 m_talebi@gmail.com Shahroud University of Medical Sciences Iran (Islamic Republic of) Patients with voulgaris acne; Age range 15-50 years; Satisfaction with the research. 15 years 50 years Both Previous burns; Severe hormonal disorders such as hypothyroidism; Chronic liver and kidney disease; Pregnancy and lactation; Doing restorative skin care like laser. L70.0 Acne vulgaris Treatment - Drugs Treatment - Drugs Intervention group:: Using Doxycycline capsula (Pars darou Company) in a double dose (200 mg/day) orally for three months in addition using Zinc sulfat tablet (Alborz company) daily (220mg/day) for three months. Control group: Using Doxycycline capsula (Pars darou Company) in a double dose (200 mg/day) orally for three months. Acne healing speed. Timepoint: Once every two weeks. Method of measurement: Skin imaging and global response assessment. Vice chancellor for research; Shahroud University medical and Sciences Approved 2018-03-05 Ethics committee of Shahroud University of Medical Sciences Shahroud University of Medical Sciences; 7 Tir squer, Shahroud Shahroud Semnan Iran (Islamic Republic of)