IRCT20090129001615N3 IRCT 2019-11-04 Esfahan University of Medical Sciences Evaluation and Comparison of the effect of Intracuff Alkalinized Lidocaine versus Intravenous Lidocaine on Coughing and Sore throat after Surgical Operation Evaluation and Comparison of Intracuff Alkalinized Lidocaine versus Intravenous Lidocaine effects on Coughing and Postoperative Sore throat 2017-10-01 anticipated 99 Complete https://irct.ir/trial/42903 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Simple randomization with Random Allocation Software, Blinding description: The patient is not aware of the Substance used during Intubation. Samples were collected by an Anesthetist unaware of the type of used Anesthetic Agents. (Administration of drugs was done by another Anesthetist.). 3 Condition 1: Coughing after intubation. Condition 2: Sore throat after intubation. Intervention 1: Intervention group: Intracuff Lidocaine Group, The population of the first group was 33. Initially, in this group, the cuff of endotracheal tube was slowly filled with air until no sound of air leakage was heard and then 2 ml of lidocaine was injected into the cuff. Finally, an additional volume of NaHCo3 8.4% was injected into the cuff to reach the pressure of 30 cmH2o inside. Intervention 2: Intervention group: Intravenous Lidocaine, the cuff of endotracheal tube was filled with air to the pressure of 30 cmH2o with air; then at the end of the surgery and after extubation 1.5 mg/kg lidocaine was injected intravenously. Intervention 3: Control group: the cuff of endotracheal tube was filled only with air to the pressure of 30 cmH2o. No - There is not a plan to make this available Justification or reason for not sharing IPD is No more information