]>
IRCT20100427003813N11 IRCT 2020-03-29 Babol University of Medical Sciences Evaluation of the effect of plasma rich in growth factors (PRGF) with sub- epithelial connective tissue graft via semilunar technique in dark triangle treatment Evaluation of the effect of plasma rich in growth factors (PRGF) with sub- epithelial connective tissue graft via semilunar technique in dark triangle treatment 2020-01-15 anticipated 16 Complete https://irct.ir/trial/42935 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients will be enter the study according to inclusion and exclusion criteria. Surgical areas are randomly divided into two groups by coin throwing method, Blinding description: Patients are unaware of which treatment group they are. The outcome measurer is different from whom that cures patients. N/A Gingival recession. Intervention 1: Intervention group: Connective tissue graft with PRGF via Semilunar technique. Intervention 2: Control group: Connective tissue graft via Semilunar technique. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Niloofar Jenabian
Ganjafrooz Ave.
Babol Iran (Islamic Republic of) 4717647745 +98 11 3220 7918 n.jenabian@mubabol.ac.ir Babol University of Medical Sciences scientific Niloofar Jenabian
Ganjafrooz Ave.
Babol Iran (Islamic Republic of) 4717647745 +98 11 3220 7918 n.jenabian@mubabol.ac.ir Babol University of Medical Sciences Iran (Islamic Republic of) Age over 18 years At least one region of an absence of papilla should be sub-type I, II of Tarnow's classification and in the Anterior Maxilla Ability to maintain proper good oral hygiene (O'LEARY plaque score<=20%) Signature of consent form 18 years no limit Both Pregnancy Coagulation problems Medications interfering with Platelet function (NSAIDs) Medications interfering with wound healing (Corticosteroid, anti-cancer) Any systemic or local disease that has a contraindication in periodontal treatment Allergic reaction to materials used in surgery Active infectious disease (hepatitis, tuberculosis and AIDS) smoking Frenum stretch in the surgical area Orthodontic patients The use of medications that are well-established causes of gingival enlargement Use of traumatic tooth brushing, abrasive tooth brushes Use of antibiotics in the past 3 months (for 2 weeks) Periodontal disease K06.0 Gingival recession Treatment - Surgery Treatment - Surgery Intervention group: Connective tissue graft with PRGF via Semilunar technique Control group: Connective tissue graft via Semilunar technique Healing index. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with healing index (HI) based on Landry index. Probing pocket depth (PPD). Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe. Esthetic Visual Analogue scale. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with Visual analogue scale. Postoperative pain. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: with Visual analogue scale. Bleeding on probing (BOP). Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe. Mesiodistal distance of dark triangle. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe. ŮŽApicocoronal distance of the dark triangle. Timepoint: On the day of surgery, 14, 30, 90, and 180 days after the surgery. Method of measurement: using a standardized periodontal probe. Babol University of Medical Sciences Approved 2020-01-11 Ethics committee of Babol univercity of medical science Ganjafrooz Ave. Babol Mazandaran Iran (Islamic Republic of)