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IRCT20191012045070N1 IRCT 2019-11-05 Ahvaz University of Medical Sciences Comparing the Effects of Furosemide, Mannitol, and Dopamine on Diuresis in Patients under Cesarean Section Comparing the effects of Furosemide, Mannitol, and Dopamine on Diuresis in Patients with Cesarean Section under Spinal Anesthesia 2019-09-23 anticipated 80 Complete https://irct.ir/trial/43263 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Individuals are randomly divided into four groups based on simple randomization method using random digits table. In this method, a collection of non-template numbers is randomly generated and arranged as a table. A collection of numbers is considered for each group and the patients are asked to select one of the table numbers. According to the selected number, they are randomly assigned to one of the intervention or control groups, Blinding description: Participants are informed about the purpose and method of study. After receiving informed consent, they are blinded to the study groups to unify patients in terms of their empathy sense. Researchers responsible for data collection and analyses will also blinded to the groups allocation for preventing personal viewpoint. 3 Cesarean Section. Intervention 1: Intervention group (1): Patients are received 100 ml 20% mannitol serum intravenously for the last 30 min of the surgery. Intervention 2: Intervention group (2): Patients are received infusion of 0.25 mg/kg of furosemide in 500 cc normal saline serum for 30 min of the surgery. Intervention 3: Intervention group (3): Patients are received a renal dose of 0.25 to 2 μg/kg/min dopamine in 500 cc of normal saline serum. Intervention 4: Control group: Patients are received 500 cc normal saline serum without any drug for 30 min. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Ali Hasani Gohargan
Imam Khomeini Hospital, Azadegan Ave.
Ahvaz Iran (Islamic Republic of) 6135715794 009861329235893 Hasani.a@ajums.ac.ir Ahvaz University of Medical Sciences scientific Kaveh Behaeen
Imam Khomeini Hospital, Azadegan Ave.
Ahvaz Iran (Islamic Republic of) 6135715794 009861322235292 drbehaeen@yahoo.com Ahvaz University of Medical Sciences Iran (Islamic Republic of) Age group 18 to 45 years Complete pregnancy period (based on weeks) 18 years 45 years Female Patients with acute renal failure with inadequate cardiac output and tissue perfusion Dialysis-dependent patients Not having normal levels of creatinine and BUN O82.8 Other single delivery by caesarean section Treatment - Drugs Treatment - Drugs Treatment - Drugs Treatment - Drugs Intervention group (1): Patients are received 100 ml 20% mannitol serum intravenously for the last 30 min of the surgery. Intervention group (2): Patients are received infusion of 0.25 mg/kg of furosemide in 500 cc normal saline serum for 30 min of the surgery. Intervention group (3): Patients are received a renal dose of 0.25 to 2 μg/kg/min dopamine in 500 cc of normal saline serum. Control group: Patients are received 500 cc normal saline serum without any drug for 30 min. Urine output volume. Timepoint: 0 (immediately after admission to recovery room), 2 and 6 hours after the completion of the surgical operation. Method of measurement: Urine output volume based on CC. Ahvaz University of Medical Sciences Approved 2019-06-08 Ethics committee of Ahvaz University of Medical Sciences Research deputy, Ahvaz Jundishapur University Of Medical Sciences, Golestan Blvd. Ahvaz Khouzestan Iran (Islamic Republic of)