IRCT20180717040509N3 IRCT 2020-03-27 Mazandaran University of Medical Sciences Comparison of pre-emptive metoclopramide and ondansetron on patients' pain, discomfort and nausea Comparison of pre-emptive metoclopramide and ondansetron on patients' pain, discomfort and nausea associated with NG Tube insertion 2017-08-23 anticipated 46 Complete https://irct.ir/trial/43465 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization with Independent samples. The 46 sample units were divided into two independent groups with equal volume according to the random number table. Random Unit: individual; random tool: Random Number Table, Blinding description: Participants, physicians, nurses, and patient evaluators are not aware of the group allocation. 3 Pain, nausea and discomfort from nasal-gastric tube insertion. Intervention 1: Intervention group 1: for the intervention group 15 minutes before NG tube placement, 10 mg Ondansetron (manufactured by Alawi Pharmaceutical Company) injected intravenously. Intervention 2: Intervention group 2: for the intervention group 15 minutes before NG tube placement, 10 mg Metoclopramide (manufactured by Alawi Pharmaceutical Company) injected intravenously. Intervention 3: Control group: patients in the control group received 10 mg of normal saline (as placebo) 15minutes before NG tube placement. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information