IRCT20191124045482N1 IRCT 2019-12-28 Mashhad University of Medical Sciences The effects of hypo-caloric and full-caloric enteral feeding on metabolic stress indices of patients with multiple trauma, during the first week of admission in the general intensive care unit The effects of hypo-caloric and full-caloric enteral feeding on metabolic stress indices of patients with multiple trauma, during the first week 2020-01-05 anticipated 80 Complete https://irct.ir/trial/43735 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: For randomization, the permuted block randomization method with blocks of size 4 is used. According to the sample size of 80, 20 blocks of size four will be produced using the online site (www.sealedenvelope.com), Blinding description: After conscious reporting from the patient or their companions, the patient is randomly assigned to either hypo-caloric and full-caloric enteral feeding. N/A multiple truama. Intervention 1: Intervention group: Patients in the intervention group will receive Hypocaloric diet. Subjects of hypocaloric diet group will receive 40 -30 percent of calculated calorie by using indirect calorimetry device during the first 24-48 hours of being in patient, and this amount will be reach to70-80 percent of patient’s need in one week. Patients in the intervention group will be fed 70-80% of their required calories by the end of the intervention (day 14 of hospitalization). Intervention 2: Control group: Patients in the Control group will receive full-calorie diet. Subjects of full-calorie diet group will receive 70-80 percent of calculated calorie by using indirect calorimetry device during the first 24-48 hours of being in patient, and this amount will be reach to90-95 percent of patient’s need in one week. Patients in the Control group will be fed 90-95% of their required calories by the end of the intervention (day 14 of hospitalization). Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information