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IRCT20170112031893N6 IRCT 2020-01-06 Ghoum University of Medical Sciences Evaluation the effect of Crocus sativus extract on prevention of nephropathy induced by coronary angiograpy Evaluation the effect of Crocus sativus extract on prevention of nephropathy induced by coronary angiograpy : A triple blind randomized placebo controlled trial 2019-12-22 anticipated 120 Complete https://irct.ir/trial/43959 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients will be randomly allocated into two groups using random numbers table developed by Random Allocation Software, Blinding description: In this study, patients, statistical analyst and physicians are not aware of the allocation of drugs and placebo, and someone outside the group is aware of the allocation of treatment.The placebo is a combination of starch with edible color that is similar to the saffron capsule. 3 Contract induced nephropathy. Intervention 1: Intervention group: Treatment group with saffron extract capsule (containing 1 gram) for 5 days before angiography. Intervention 2: Control group: Placebo group with starch capsule (containing 1 gram) for five days before angiography. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is With attention due to the type of study and publication of the article, there was no need to mention this
public Seyyed Fakhreddin Hejazi
Clinical Research Development Center, Shahid Beheshti Hospital, Shahid Beheshti Blvd, Azadegan Sq, Qom, Iran
Qom Iran (Islamic Republic of) 3719976739 009832854011 Huqom1394@yahoo.com Ghoum University of Medical Sciences scientific Hosseın Yusefi
Clinical Research Development Center, Shahid Beheshti Hospital, Shahid Beheshti Blvd, Azadegan Sq, Qom, Iran
Qom Iran (Islamic Republic of) 3713649373 +98 25 3886 0146 driran1390@yahoo.com Ghoum University of Medical Sciences Iran (Islamic Republic of) patients undergo elective coronary angiography 12 years 90 years Both pre-existing end-stage renal disease requiring dialysis cardiogenic shock serum creatinine level above 5 mg/dl N14.1 Nephropathy induced by other drugs, medicaments and biological substances Treatment - Drugs Treatment - Drugs Intervention group: Treatment group with saffron extract capsule (containing 1 gram) for 5 days before angiography Control group: Placebo group with starch capsule (containing 1 gram) for five days before angiography Serum creatinin. Timepoint: 3 Day before angiograohy and 3 day after angiography. Method of measurement: blood sample. Ghoum University of Medical Sciences Approved 2019-11-05 Ethics committee of Qom University of Medical Sciences Vice chancellor for research of Qom University of Medical Sciences, Safashar road, Qom, Iran Qom Ghoum Iran (Islamic Republic of)