IRCT20170408033291N3 IRCT 2019-12-30 Qazvin University of Medical Sciences Comparison the effects of Dexmedetomidine and Labetalol on blood pressure in maxillofacial fractures surgery Comparison the effects of Dexmedetomidine and Labetalol for induced hypotension in maxillofacial fractures surgery 2018-12-22 anticipated 60 Complete https://irct.ir/trial/44028 interventional Randomization: Not randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Blinding description: Equal numbers of red and green cards representing the two groups under study are placed in a container and the patient selects a card from the container before entering the operating room. The type of intervention is determined by the color of the card selected. The patient, clinical caregiver, outcome assessor, and statistician were unaware of the study codes. 3 Fracture of mandible. Intervention 1: First intervention group: Patients in the first group receive dexmedetomidine with bolus infusion of 1µg/kg/h and maintenance dose of 3.0 -5.0 µg/kg/h. Intervention 2: Second intervention group: Patients in the second group receive infusion of labetalol with bolus dose of 0.3 mg/kg/h and maintenance dose of 0.2-0.5 mg/kg/h . Yes - There is a plan to make this available What will be shared: All data is potentially shareable after people are unrecognizable. When: Start of access period from 1399 To whom: Data will be available only to researchers working in academic and research institutions. Conditions: For further research or meta-analysis Where to obtain: Dr. Ali Alizadeh Email Address: a.alizadeh@qums.ac.ir How to obtain: Permission from Vice-Chancellor for Research and Technology Affairs of Qazvin University of Medical Sciences Comments: