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IRCT20121216011763N44 IRCT 2020-02-27 Esfahan University of Medical Sciences The effect of soy isoflavones in migraine The effect of soy isoflavones supplementation on symptoms of headache and CGRP in women with migraine 2020-02-20 anticipated 88 Complete https://irct.ir/trial/44422 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The total number of samples randomly will be divided into two groups by random blocks and each group will consist of 44 persons. The blocking method will be used for randomization. To do this, a random allocation sequence will be created through the reputable website https://www.sealedenvelope.com/simple-randomiser/v1/lists, Blinding description: Both the supplement and the placebo are similar in appearance and are labeled by a research team member who is not involved in the intervention and evaluation, thus the researcher directly involved in the evaluation and intervention is not aware of the nature of the prescribed supplement and patients are also unaware of the type of supplement they receive. 3 migraine. Intervention 1: Intervention group: Eat one soybean daily with food for eight weeks. Intervention 2: Control group: One placebo (50 mg of starch) daily with food for 8 weeks. Yes - There is a plan to make this available What will be shared: Major part of information will be available for population. When: 12 months after publication To whom: Available for people working in academic institutions Conditions: To conduct similar studies Where to obtain: Dr. Gholamreza Askari askari@mui.ac.ir How to obtain: The data will send as soon as possible, after receiving the request. Comments:
public Gholamreza Askari
Hezarjarib Ave.
Isfahan Iran (Islamic Republic of) 8174673461 +98 31 1792 2110 askari@mui.ac.ir Esfahan University of Medical Sciences scientific maede babapour golafshani
Hezar jarib
Isfahan Iran (Islamic Republic of) 8317745181 +98 31 4525 1696 babapour.matiii@gmail.com Esfahan University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Women from the age of 18 to menopause Diagnosis of migraine by a neurologist Willing to work with the project 18 years 50 years Female With breast cancer and endometrial cancer Problem or risk of breast or endometrial cancer in a breast examination by a gynecologist Having a family history of endometrial and breast cancer OCP medication use G43 Migraine Treatment - Drugs Placebo Intervention group: Eat one soybean daily with food for eight weeks Control group: One placebo (50 mg of starch) daily with food for 8 weeks Migraine symptoms (severity, frequency, duration of migraine). Timepoint: At baseline and after eight weeks. Method of measurement: Questionnaire. Serum levels of calcitonin-associated peptide (CGRP). Timepoint: At baseline and after eight weeks. Method of measurement: Laboratory analysis (blood test). Depression, stress, anxiety. Timepoint: At baseline and after eight weeks. Method of measurement: DASS-21questionnaire. Quality of Life in Migraine Patients. Timepoint: Quality of Life in Migraine Patients. Method of measurement: Migraine –Specific Quality of Life(MSQ)questionnaire. Esfahan University of Medical Sciences Approved 2019-12-23 Ethics committee of Isfahan University of Medical Sciences Hezar Jarib esfahan Isfehan Iran (Islamic Republic of)