IRCT20141009019470N100 IRCT 2020-07-18 Shiraz University of Medical Sciences The effect of Dexmedetomidine on Quality of Recovery after simple mastectomy under General anesthesia The effect of Dexmedetomidine on Quality of Recovery after simple mastectomy under General anesthesia 2020-08-10 anticipated 110 Complete https://irct.ir/trial/44433 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients were divided into two groups of 55, using the table from www.randomization.org.Patients are divided into groups A and B and treated according to their group, Blinding description: The dexmedetomidine infusion will begin thirty minutes before the end of surgery in the first group. In the second group, 0.9% normal saline infusion will begin 30 minutes before the surgery. While the anesthesiology nurse who provides dexmedetomidine and normal saline syringes and gives them to the anesthesiology resident in the operating room is unaware of the study groups. Data collection is done in the recovery and ward by nursing staff who is unaware of the amount of medication received in the groups . 2-3 Mastectomy. Intervention 1: Intervention group:30 minutes before surgery, dexmedetomidine infusion will start at a dose of 0.4 mcg / kg. Intervention 2: Control group:The 0.9% normal saline infusion will start at 0.1 cc / kg 30 min before surgery. No - There is not a plan to make this available Justification or reason for not sharing IPD is Its against our policies.