IRCT20190914044766N1 IRCT 2020-01-28 High Institute for Research and Education in Transfusion Medicine Graft versus host disease prevention/reduction by microbiome and patient blood management in allogeneic hematopoietic stem cell transplant patients Graft versus host disease prevention/reduction by microbiome and patient blood management in allogeneic hematopoietic stem cell transplant patients 2020-01-21 anticipated 40 Complete https://irct.ir/trial/44531 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: Patients were randomly divided into control and intervention groups Based on random number table   We assign a number to each patient based on the time patients visit and perform randomization using a random number table. 3 Condition 1: graft versus host disease. Condition 2: acute graft versus host disease. Intervention 1: Intervention group: Intervention group:20 Patients reported for allogeneic bone marrow transplantation: who consume one day of graft probiotic capsule daily for 21 days before transplantation until the day of transplantation./It should be noted that familact is a probiotic and prebiotic compound containing 7 strains of beneficial bacteria (Lactobacillus, Bifidobacteria and Streptococcus thermophilus) plus Prebiotic Fructoaligosaccharide). Intervention 2: Control group: 20 patients reported for allogeneic bone marrow transplantation and not taking any additional medication. Yes - There is a plan to make this available What will be shared: Information on the main outcome is added and published When: The publication begins after the paper is published after the research is completed To whom: Information will be made available to all researchers Conditions: Use of published articles from this study , For more details and details, please contact the corespondent author of the paper published in this research Where to obtain: Ehsan Yazdandoust yazdandouste@gmail.com 09107434515 Corresponding author of published research articles How to obtain: After contacting the information provider, the information will be made available to the applicant within two weeks. This will be the posting of the information after the articles are published Comments: Most of the essential information was provided to the researchers by the publication of the article