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IRCT20191230045945N1 IRCT 2020-01-12 Islamic Azad University "Effect of cardiac rehabilitation in CABG patients" CABG The effect of eight weeks cardiac rehabilitation program on lxr gene expression and serum tnf level in cabg patients 2019-10-30 anticipated 24 Complete https://irct.ir/trial/44668 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Randomization description: In this study, each person in the target population was assigned a card number and then put all the cards in a box and after mixing them into the box, randomly and without any special sequence of numbers. Drag and drop the two groups of exercise and control. N/A Atherosclerosis_CABG. Intervention 1: Intervention group: In this group, 12 cabgg men underwent eight weeks of strength and aerobic rehabilitation program in Javad Al-e-Ameh Hospital in Mashhad. They will be examined by ELISA and real_time pcr. Intervention 2: Control group: In this group, 12 patients without cardiac rehabilitation program were considered as the comparison group. Blood samples were taken from the patients before and after the beginning of the study to evaluate tnf alpha and lxr and were compared. Yes - There is a plan to make this available What will be shared: Only the main part related to the original consequence is shared after unidentifiable. When: The period of access to documentation and data files is one year after the results are published To whom: Access for researchers working in academic institutions Conditions: No special conditions. Where to obtain: Refer to responsible author by email How to obtain: It will be requested through the email address and will be tracked as soon as possible Comments:
public Fahimeh Parhizi
Iqbal Lahori Boulevard;
Mashhad Iran (Islamic Republic of) 1111111111 +98 51 3502 9210 Parhizif1@mums.ac.ir Islamic Azad University scientific Fahimeh Parhizi
Mashhad.eghbal lahouri blv.25 street.number 29
Mashhad Iran (Islamic Republic of) 1111111111 +98 51 3502 9210 Parhizif1@mums.AC.IR Islamic Azad University Iran (Islamic Republic of) Men age 40_60. Cognitive, visual and auditory health. No systolic blood pressure greater than 160 mmHg and diastolic higher than 100mmHg. Not using walking aids like walking canes and walkers. Avoid doing exercise or exercise activities while participating in research. 45 years 60 years Male Having dangerous arrhythmias and ECG changes Severe respiratory problems that prevent you from exercising I25.708 Atherosclerosis and coronary artery bypass graft(s) Rehabilitation Rehabilitation Intervention group: In this group, 12 cabgg men underwent eight weeks of strength and aerobic rehabilitation program in Javad Al-e-Ameh Hospital in Mashhad. They will be examined by ELISA and real_time pcr. Control group: In this group, 12 patients without cardiac rehabilitation program were considered as the comparison group. Blood samples were taken from the patients before and after the beginning of the study to evaluate tnf alpha and lxr and were compared. Lxr gene expression. Timepoint: 24 hour before the start of the rehabilitation period and 48 hour after the end of the cardiac rehabilitation period. Method of measurement: 10 ml of blood was collected from the brachial vein of the participants and measured by a Real-time polymerase chain reaction in the laboratory. Tnf alpha. Timepoint: 24 hour before the start of the rehabilitation period and 48 hour after the end of the cardiac rehabilitation period. Method of measurement: 10 ml of blood was collected from the brachial vein of the participants and measured by elisa in the laboratory. Islamic Azad University Approved 2019-07-18 Ethics committe of Azad eslamic university of neyshapior Eghbal lahouri blv.25 street. No.29 Mashhad Razavi Khorasan Iran (Islamic Republic of)