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IRCT20130730014217N2 IRCT 2020-02-22 Esfahan University of Medical Sciences The efficacy of Vitamin D3 on seizure attacks in the patients with drug-resistant epilepsy Effect of Vitamin D3 on seizure attacks in the patients with drug-resistant epilepsy compared with the control group 2018-04-04 anticipated 40 Complete https://irct.ir/trial/44699 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The simple randomized blocking method was performed among patients with epilepsy referred to teaching hospitals and epilepsy clinics in Isfahan individually. SPSS software was used for this purpose, Blinding description: Patients were first invited and interviewed about the research and written consent was obtained. Patients were unaware of which group they were in, and they only took the prescribed medication. But the researcher knew which patient group he was in. 3 drug-resistant epilepsy. Intervention 1: Control group: 22 patients with refractory epilepsy who received placebo at the Faculty of Pharmacy of Isfahan for 8 weeks and once a week. Intervention 2: Intervention group: Twenty-two patients with refractory epilepsy who were treated with Pearl Vitamin D3 for fifty thousand units weekly for 8 weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is Patients' personal information.
public Mohammadreza Najafi
Daneshgah
Esfahan Iran (Islamic Republic of) 7346181746 +98 31 3627 3910 najafi@med.mui.ac.ir Esfahan University of Medical Sciences scientific Mohammadreza Najafi
Daneshgah
Esfahan Iran (Islamic Republic of) 7346181746 +98 31 3627 3910 najafi@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) drug-resistant epilepsy to treatment No other disease Vitamin D3 deficiency Adult population over 18 years. 18 years no limit Both Patient's unwillingness and conscious dissatisfaction G40.211 Localization-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures, intractable, with status epilepticus Placebo Treatment - Drugs Control group: 22 patients with refractory epilepsy who received placebo at the Faculty of Pharmacy of Isfahan for 8 weeks and once a week. Intervention group: Twenty-two patients with refractory epilepsy who were treated with Pearl Vitamin D3 for fifty thousand units weekly for 8 weeks. Number of seizures. Timepoint: At beginning and 1, 2 and 3 months after treatment, patients were visited and the number and duration of seizures occurred. Method of measurement: Blood test and evaluation of 25OH vitamin D. Esfahan University of Medical Sciences Approved 2017-03-02 Ethics Committee of Isfahan University of Medical Sciences Ethics Committee of Isfahan University of Medical Sciences, Isfahan University of Medical Sciences, Hezar jrib street, Isfahan, Iran Isfahan Isfehan Iran (Islamic Republic of)