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IRCT20190517043610N1 IRCT 2020-02-15 Kerman University of Medical Sciences The Effect of Carboxy Therapy on Vitiligo Treatment Evaluation of carboxy therapy efficacy with NB-UVB phototherapy compared with NB-UVB phototherapy alone in patients with vitiligo 2019-06-22 anticipated 30 Complete https://irct.ir/trial/44704 interventional Randomization: N/A, Blinding: Double blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Blinding description: Evaluation of patients by an evaluating physician who has no treatment information is performed at the end of treatment and patients are unaware of the type of treatment. N/A Vitiligo. Intervention 1: The patient will be treated with phototherapy three times a week according to the protocol. In each patient, one lesion undergoes carboxy therapy and carboxy therapy is performed weekly for 16 weeks. The rate of gas infusion is 50 cc / min and the total amount of gas injected in each lesion is 3 cc and the median time of each session is 5 to 8 minutes. Intervention 2: Control group: Patient with bilatral vitiligo lesions treated with protocol three times a week according to protocol. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Saiede Farajzade
Emam Khomeini blvd,Afzalipor Hospital
Kerman Iran (Islamic Republic of) 7616913991 +98 34 3132 8000 Safaderm@yahoo.com Kerman University of Medical Sciences scientific Saiede Farajzade
Emam Khomeini Blvd,Afzalipor Hospital
Kerman Iran (Islamic Republic of) 7616913911 +98 34 3132 8000 Safaderm@yahoo.com Kerman University of Medical Sciences Iran (Islamic Republic of) Vitiligo disease with sympathetic involvement on both sides of the body 18 years no limit Both Photosynthetic Diseases Segmental vitiligo Autoimmune Disease Use of other vitiligo treatments such as topical corticosteroids and topical calcineurin. Patient with positive Kobner history and previous history of colloid formation pregnancy and lactation malignancy Infection at the injection site Severe ischemic heart disease, acute embolism, thrombophlebitis, gangrene, history of stroke renal failure hypertension Use of carbonic anhydrase inhibitors (acetazolamide, diclofenac) Decreased plasma protein levels in chronic hepatic failure L80 Vitiligo Treatment - Devices Treatment - Devices The patient will be treated with phototherapy three times a week according to the protocol. In each patient, one lesion undergoes carboxy therapy and carboxy therapy is performed weekly for 16 weeks. The rate of gas infusion is 50 cc / min and the total amount of gas injected in each lesion is 3 cc and the median time of each session is 5 to 8 minutes. Control group: Patient with bilatral vitiligo lesions treated with protocol three times a week according to protocol Skin pigmentation of lesions. Timepoint: Before treatment and one month, two months, three months and four months after treatment. Method of measurement: Questionnaire designed by the researcher. Kerman University of Medical Sciences Approved 2019-07-07 Ethics committee of kerman University of Medical Sciences Emam khomeini blvd,kerman town Kerman Kerman Iran (Islamic Republic of)