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IRCT20200105046012N1 IRCT 2021-01-03 Zahedan University of Medical Sciences Evaluation of relationship between vitamin D supplementation treatment and hypercalciuria in patients with kidney stones Evaluation of relationship between vitamin D supplementation treatment and hypercalciuria in patients with kidney stones 2020-01-21 anticipated 90 Complete https://irct.ir/trial/44832 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Randomization of patients will be done by the responsible researcher using a table of random numbers Randomization will be recorded on an Excel file by the principal investigator. Participants will be randomized via permuted block randomization. Each block will be consistent of sizes of 4 patients. For assignment of each patient to the drug or placebo group, for each patients a unique code consistent of 2 letters and a digit will be assigned. the code will be unique for each patient ( for example code AB1 for first patient). Only the principle investigator will be informed of the assignment of each code to the medication or placebo group, Blinding description: 1- The nurse who gives the medication to the patients whether or not they are on the medication is not aware Patients were or were not aware of the drug 3. The laboratory does not know which sample belongs to the control group. 3 Hypercalciuria in patients with kidney stones. Intervention 1: Intervention group: People with kidney stones who have vitamin D levels below 30 ng / ml are prescribed oral vitamin D 50,000 units weekly for up For each patient, training sessions are held before and after the intervention, and in this study, the product of Zahravi Company is used.to 8 weeks. Intervention 2: Control group: People with kidney stones who have vitamin D levels below 30 ng / ml are given weekly placebo for up to 8 weeks.For each patient, training sessions are held before and after the intervention, and in this study, the product of Zahravi Company is used. Yes - There is a plan to make this available What will be shared: The whole potential data is unpublished after being unidentifiable When: Start the access period 6 months after printing the results To whom: Only available to scholars working in academic and academic institutions Conditions: Use of study data is permitted for any use by researchers working in academic and scientific institutions Where to obtain: Ali ebn Abitalib Hospital, Zahedan, Department of intral Deputy of Research of Zahedan University of Medical Sciences, Faculty of Medicine Dr. Ali Alidadi, professor of the thesis, telephone number 09120621590 How to obtain: It takes about 1 month from the request of the applicant to access data files or time documentation Comments:
public elham javadian
Ali Bin Abi Talib Hospital ., Persian Gulf Highway ., Zahedan town ., sistan and Baluchestan province
zahedan Ireland 9816743111 +98 54 3329 5575 elham.javadian1396@zaums.ac.ir Zahedan University of Medical Sciences scientific elham javadian
Ali Bin Abi Talib Hospital ., Persian Gulf Highway ., Zahedan town ., sistan and Baluchestan province
Zahedan Ireland 9816743111 05433295570 elham.javadian1396@zaums.ac.ir Zahedan University of Medical Sciences Iran (Islamic Republic of) - Patients with kidney stones and vitamin D deficiency referred to Zahedan Nephrology Clinic - People aged 18-65 years Acceptance to participate in the project Lack of specific illnesses such as heart failure, kidney or liver disease Absence of inflammatory or infectious diseases Not taking medications like diuretics Not taking corticosteroids Not taking immunosuppressive drugs Not taking vitamin D supplement before study 18 years 65 years Both - Medication including drugs such as diuretics, potassium citrate - Pregnant women - Recent stone disposal Ureteral stone leads to obstruction Urinary tract infection for the last two weeks - Systemic infection in the last two weeks Treatment - Drugs Placebo Intervention group: People with kidney stones who have vitamin D levels below 30 ng / ml are prescribed oral vitamin D 50,000 units weekly for up For each patient, training sessions are held before and after the intervention, and in this study, the product of Zahravi Company is used.to 8 weeks. Control group: People with kidney stones who have vitamin D levels below 30 ng / ml are given weekly placebo for up to 8 weeks.For each patient, training sessions are held before and after the intervention, and in this study, the product of Zahravi Company is used. Increased urinary calcium level. Timepoint: 24-hour urine calcium measurement at baseline (before intervention) and 3 months after intervention. Method of measurement: Laboratory measurement. Zahedan University of Medical Sciences Approved 2020-01-04 Ethics committee of zahedan University of Medical Sciences Sistan and Baluchestan Zahedan - Persian Gulf Highway - Imam Khomeini Mosque - Ali Bin Abi Talib Hospital Zahedan Sistan-va-Balouchestan Iran (Islamic Republic of)