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IRCT20200116046154N1 IRCT 2020-02-11 Razi University Anti-atherosclerosis effects of 12 weeks high intensity interval and aerobic training on serum levels salusin-α and -β, nitric oxide, inflammatory markers and lipid profile in overweight and obese childrens Anti-atherosclerosis effects of 12 weeks high intensity interval and aerobic training on serum levels salusin-α and -β, nitric oxide, inflammatory markers and lipid profile in overweight and obese childrens 2018-07-23 anticipated 45 Complete https://irct.ir/trial/45099 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Forty-five subjects from 20 schools participated in the study and were randomly divided into 3 groups of HIIT, aerobic and control groups. Randomization of the study groups was performed using simple or unlimited randomization by using dice such that the numbers 1 and 2 for the first group, 3 and 4 for the second group, and 5 and 6 for the third group were considered. Were taken. N/A Anti-Atherosclerosis Effects of exercise. Intervention 1: Intervention group: A briefing was held to familiarize children with the exercise protocol and to measure anthropometric parameters such as height, weight, body mass index, waist and hip circumference, subcutaneous fat thickness. Twenty-four hours after the briefing session, a field test for children or a shuttle ride test was performed to measure aerobic fitness and maximal aerobic speed. 72 hours after the shuttle test, the first blood sample was taken at 7:30 am to 8 am after 12 hours in fasting HIIT subjects to measure the components of the study. 48 hours after blood sampling in the HIIT subjects according to their intended severity and their specific distances obtained by calculating their maximum aerobic velocity and determined by the cones for each subject separately, 100 to 120% of maximal aerobic speed were trained 3 times a week for 12 weeks. Intervention 2: Intervention group: A briefing was held to familiarize children with the exercise protocol and to measure anthropometric parameters such as height, weight, body mass index, waist and hip circumference, subcutaneous fat thickness. Twenty-four hours after the briefing session, a field test for children or a shuttle run test was performed to measure aerobic fitness and maximal aerobic speed. 72 hours after the shuttle test, the first blood samples were taken at 7:30 am to 8 am after 12 hours of fasting in the aerobic exercise group to measure the components of the study. 48 hours after blood sampling, aerobic group subjects were also warmed up and stretched according to the intensity and duration of the study, based on 40-70% of heart rate reserve 3 sessions per week. They practiced for 12 weeks. Intervention 3: Control group: A briefing was held to familiarize children with the exercise protocol and to measure anthropometric parameters such as height, weight, body mass index, waist and hip circumference, subcutaneous fat thickness. 72 hours after the briefing, the first blood sample was taken at 7:30 am to 8 am after 12 hours in the fasting state of the control group to measure the research components. The control group continued their normal routine throughout the 12 weeks of the study, and was advised not to engage in any organized exercise. Yes - There is a plan to make this available What will be shared: The individual data of the study participants are shared after unidentifiable individuals are identified When: Two month To whom: Researchers Conditions: For the sake of transparency and researcher satisfaction Where to obtain: Alireza Paahoo How to obtain: Request and send to researcher Comments:
public Vahid Tadibi
Room no.67, Faculty of Physical Education and Sport Sciences, Razi University, Zakariya Razi Blvd.
Kermanshah Iran (Islamic Republic of) 6714414971 +98 83 3427 9265 vtadibi@yahoo.com Razi University scientific Vahid Tadibi
Room no.67, Faculty of Physical Education and Sport Sciences, Razi University, Zakariya Razi Blvd.
Kermanshah Iran (Islamic Republic of) 6714414971 +98 83 3427 9265 vtadibi@yahoo.com Razi University Iran (Islamic Republic of) Ages 9 to 12 years Body mass index between 19.1-26.2 No drug treatment ِNO chronic diseases such as diabetes, metabolic syndrome (systolic blood pressure 130 mm Hg or diastolic blood pressure 85 mm Hg, waist circumference greater than 102 cm and fasting glucose 110 mm Hg), hormone, orthopedic Not participating in any regular training program (except for exercise ring) within 6 months prior to entering the study The subjects must be boys 9 years 12 years Male Voluntary withdrawal by participants for any reason. Acute infectious diseases such as influenza during research. Two consecutive absentee sessions and three non-consecutive sessions during the time of the research run. Acute Injury Due to Practice During Research. N/A N/A N/A Intervention group: A briefing was held to familiarize children with the exercise protocol and to measure anthropometric parameters such as height, weight, body mass index, waist and hip circumference, subcutaneous fat thickness. Twenty-four hours after the briefing session, a field test for children or a shuttle ride test was performed to measure aerobic fitness and maximal aerobic speed. 72 hours after the shuttle test, the first blood sample was taken at 7:30 am to 8 am after 12 hours in fasting HIIT subjects to measure the components of the study. 48 hours after blood sampling in the HIIT subjects according to their intended severity and their specific distances obtained by calculating their maximum aerobic velocity and determined by the cones for each subject separately, 100 to 120% of maximal aerobic speed were trained 3 times a week for 12 weeks. Intervention group: A briefing was held to familiarize children with the exercise protocol and to measure anthropometric parameters such as height, weight, body mass index, waist and hip circumference, subcutaneous fat thickness. Twenty-four hours after the briefing session, a field test for children or a shuttle run test was performed to measure aerobic fitness and maximal aerobic speed. 72 hours after the shuttle test, the first blood samples were taken at 7:30 am to 8 am after 12 hours of fasting in the aerobic exercise group to measure the components of the study. 48 hours after blood sampling, aerobic group subjects were also warmed up and stretched according to the intensity and duration of the study, based on 40-70% of heart rate reserve 3 sessions per week. They practiced for 12 weeks. Control group: A briefing was held to familiarize children with the exercise protocol and to measure anthropometric parameters such as height, weight, body mass index, waist and hip circumference, subcutaneous fat thickness. 72 hours after the briefing, the first blood sample was taken at 7:30 am to 8 am after 12 hours in the fasting state of the control group to measure the research components. The control group continued their normal routine throughout the 12 weeks of the study, and was advised not to engage in any organized exercise. Salusin-α. Timepoint: Pre and Post test. Method of measurement: Blood sampling and laboratory kit. Salusin-β. Timepoint: Pre and Post test. Method of measurement: Blood sampling and laboratory kit. Nitric oxide. Timepoint: Pre and Post test. Method of measurement: Blood sampling and laboratory kit. Interleukin-6. Timepoint: Pre and Post test. Method of measurement: Blood sampling and laboratory kit. C-reactive protein. Timepoint: Pre and Post test. Method of measurement: Blood sampling and laboratory kit. Lipid profile. Timepoint: Pre and Post test. Method of measurement: Blood sampling and laboratory kit. Razi University Razi University Razi University Approved 2019-01-30 Kermanshah University of Medical Sciences Shahid Beheshti Boulevard Kermanshah Kermanshah Iran (Islamic Republic of)