IRCT20200127046282N1 IRCT 2020-04-19 Vice chancellor for research, Shahid Beheshti University of Medical Sciences , Loghman Hospital effect of administration of intrathecal Dexmedetomidine on the Spinal Cord Mori Evaluating the effect of administration of intrathecal Dexmedetomidine on the Spinal Cord Mori levels of apoptotic factors in patients scheduled for lumbar disc surgery 2019-12-22 anticipated 40 Complete https://irct.ir/trial/45383 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients included in the study will be randomly divided into control and Dexmedetomidine groups based on random number table.In this way, we put a set of numbers in a completely random order without any pattern or order, set the table numbers to read from above. For intervention group we consider even numbers and for control group we consider individual numbers. Then we place one of the numbers up and down, register the number and assign it to one of the intervention or control groups. 3 Lumbar disc herniation. Intervention 1: Intervention group: After surgical incision a spinal cord fluid sample of 1 cc is taken from the site of surgery, the needle stays in place and the syringe is removed and with another syringe Dexmedetomidine is injected intrathecally.Finally, 1 cc of cerebrospinal fluid is taken again. Intervention 2: Control group: After surgical incision a spinal cord fluid sample of 1 cc is taken from the site of surgery And the needle comes out. Finally, 1 cc of cerebrospinal fluid is taken again. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information.