IRCT20180416039326N11 IRCT 2020-03-14 Esfahan University of Medical Sciences Comparison of cardiovascular response to laryngoscopy and endotracheal intubation in induction of anesthesia with etomidate and thiopental sodium - Midazolam Evaluation and comparison of cardiovascular response to laryngoscopy and endotracheal intubation in induction of anesthesia with etomidate and thiopental sodium - Midazolam 2020-03-04 anticipated 78 Complete https://irct.ir/trial/45573 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Random allocation to intervention and control groups using Random allocation software, Blinding description: In this study, the patient and observer who collects the information will not be in the course of the study, as the drug is injected by the planter, but the data will be collected by another person who is not in the study and the information will be double-blinded. 2 Cardiovascular response. Intervention 1: First intervention group: after receiving 5 ml/kg of ringer lactate and pre-oxygenation for patients, induction of anesthesia was performed including Fentanyl 2mcg/kg, Etomidate 0.3mg/kg, Atracurium 0.5 m/kg.Then patients underwent mechanical ventilation by mask for three minutes.Then the airway is protected by ETT and the patient is attached to the anesthetic machine and is mechanically ventilated and maintained anesthetized with iso-fluorine 0.8-1.2 Mac, with oxygen and N2O of 50%. Intervention 2: Second intervention group: after receiving 5 ml/kg of ringer lactate and pre-oxygenation for patients, induction of anesthesia was performed including Fentanyl 2mcg/kg, Thiopental sodium 2.5 mg/kg and Midazolam 0.075 mg/kg, Atracurium 0.5 m/kg.Then patients underwent mechanical ventilation by mask for three minutes.Then the airway is protected by ETT and the patient is attached to the anesthetic machine and is mechanically ventilated and maintained anesthetized with iso-fluorine 0.8-1.2 Mac, with oxygen and N2O of 50%. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information