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IRCT20200203046366N1 IRCT 2020-10-29 Zanjan University of Medical Sciences Efficacy of transcranial direct current stimulation(tDCS) on schizophrenia Determination of therapeutic effect of tDCS in schizophrenic patients with predominant negative symptoms 2019-06-20 anticipated 40 Complete https://irct.ir/trial/45697 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: This clinical trial consists of two groups: real and sham intervention, double blind and randomized, Randomization description: Blocked randomization, individual, layered, statistical software. A sample of 40 schizophrenic patients with dominant negative symptoms by random sampling available on the web at  https://www.sealedenvelope.com,The number of 20 binary blocks AB is assigned by the supervisor in two groups of 20, Blinding description: Patients do not know in which intervention group AB (real and sham intervention) are. 2- Data analysis is performed by the data analyzer. As they are not aware of the nature of the groups AB. All data will be encrypted. N/A Schizophrenia. Intervention 1: Actual excitation of 2 mA for 20 minutes and placement of the cathode electrode in the left DLPFC and anode in the patient's right Orbito Frontal. The intervention consists of 15 sessions per day. Intervention 2: Intervention group: The 2 mA stimulation is stopped after 60 seconds of the cathode electrode in the left DLPFC and the anode in the patient's right Orbito Frontal, the intervention consisting of 15 treatment sessions per day. Yes - There is a plan to make this available What will be shared: All of information related to main outcome will be published. When: Start the access period from 2020 To whom: Researchers and clinicians working in academic and scientific institutions Conditions: Access to documents is possible to inform other researchers and clinicians. Access to documents is possible to work with the researcher. Where to obtain: Zanjan Shahid Beheshti Hospital Psychiatry Department, Dr. Mina Shabani, Mobile: 0912744589 Zanjan Shahid Beheshti Hospital Psychiatry Department, Priya Jalili Khayavi, Mobile: 09144554389 How to obtain: Documents will be shared only when the reason for the request is announced by phone or e-mail.Response time is seven days. Comments:
public Parya Jalili Khiavi
Ark Gate, Dr. Beheshti Hospital
Zanjan Iran (Islamic Republic of) 45136-15788 +98 24 3354 4003 dr.parya.jalili@gmail.com Zanjan University of Medical Sciences scientific Parya Jalili Khiavi
Ark Gate, Dr. Beheshti Hospital
Zanjan Iran (Islamic Republic of) 45136-15788 +98 24 3354 4003 dr.parya.jalili@gmail.com Zanjan University of Medical Sciences Iran (Islamic Republic of) People diagnosed with schizophrenia on thebasis of DSM5 Patients receiving fixed antipsychotic treatment regimen for at least 4 weeks 18 years 65 years Both 1-substance dependency comorbid psychiatric disorder(including suicidal individuals) neurologic diseases such as epilepcy,CVA or cerebral vessels disease physical disease such as malignancy,infections and heart failure, pragnancy, the existence of a metal implant in the body and skin disease involving scalp F20-F29 Schizophrenia, schizotypal and delusional disorders Rehabilitation Placebo Actual excitation of 2 mA for 20 minutes and placement of the cathode electrode in the left DLPFC and anode in the patient's right Orbito Frontal. The intervention consists of 15 sessions per day. Intervention group: The 2 mA stimulation is stopped after 60 seconds of the cathode electrode in the left DLPFC and the anode in the patient's right Orbito Frontal, the intervention consisting of 15 treatment sessions per day. Positive and negative symptoms of schizophrenia. Timepoint: Pre-test, Post-test and follow up (one month after post-test). Method of measurement: Positive and Negative Syndrome Scale. Negative Symptoms. Timepoint: Pre-test, Post-test and follow up (one month after post-test). Method of measurement: Scale for the Assessment of Negative Symptoms. Depression. Timepoint: Pre-test, Post-test and follow up (one month after post-test). Method of measurement: Calgary Depression Scale for Schizophrenia. Zanjan University of Medical Sciences Approved 2019-06-10 Ethics committee of Zanjan University of Medical Sciences Azadi Square, Zanjan University of Medical Sciences Zanjan Zanjan Iran (Islamic Republic of)