IRCT20170903036045N2 IRCT 2020-04-17 Tehran University of Medical Sciences Preparation, evaluation and comparison of two topical semisolid formulations containing insulin for improvement and acceleration of diabetic wound. Preparation, evaluation, and comparison of two topical semisolid formulations containing insulin for improvement and acceleration of diabetic wound. 2020-03-10 anticipated 20 Complete https://irct.ir/trial/45852 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2 Diabetic wounds. Intervention group: 1) Wound should be washed with sterile NS or sterile water after wearing sterile gloves. 2) If there is any necrosis, debridement should be done gently by sterile gauze pads (wet with sterile NS). 3) After washing, wounds should be allowed to dry in room atmosphere 4) Wound should not be dried by using any gauze or other means 5) A 0.5 mm thick layer of insulin gel (100 IU per mL of insulin) should be applied on the surface of the wound without any contact with the hand or another applicator 6) A suitable piece of sterile Gauze layers should be placed on the surface of the wound and be dressed by anti-allergic 3M tape.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information.