IRCT20120215009014N352 IRCT 2020-04-21 Shahid Beheshti University of Medical Sciences Comparison of the effectiveness of the three methods: healing with dry amniotic dressing, dressing with platelet derived growth factor, and conventional surgical debridement on the improvement of diabetic foot ulcer Comparison of the effectiveness of the three methods: healing with dry amniotic dressing, dressing with platelet derived growth factor, and conventional surgical debridement on the improvement of diabetic foot ulcer: a randomized clinical trial 2020-05-04 anticipated 123 Complete https://irct.ir/trial/47124 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The patients will be randomly assigned to intervention and control groups using block randomization. For this purpose, we will prepare six sheets of paper, writing on two sheets the name of the intervention 1 and on two other sheets the name of the intervention 2 and on the third two sheets the name of the control. The paper sheets will be pooled, placed in a container, and randomly drawn one at a time for each patient without replacement until all six sheets are drawn. The six paper sheets will be then placed back into the container, and this action repeated until the sample size is reached. 2 Diabetic foot ulcer. Intervention 1: Intervention group 1: Wound irrigation and then healing with dry amniotic dressing daily for 10 weeks. Intervention 2: Intervention group 2: Wound irrigation and then dressing with platelet derived growth factor daily for 10 weeks. Intervention 3: Control group: Wound irrigation and then conventional surgical debridement daily for 10 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It depends on the situations and the results of the study as well as the approval of the financial supporting