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IRCT20200217046523N1 IRCT 2020-06-18 Esfahan University of Medical Sciences Preventive Effects of Ketorolac and Nephaazolin- Anthrazoline Drops on Reducing Patient's Ocular Complications Evaluation on the Preventive Effects of Ketorolac and Nephaazolin- Anthrazoline Drops on Reducing Patient's Ocular Complications after Phacoamulsification Surgery under sedation 2020-08-19 anticipated 54 Complete https://irct.ir/trial/47208 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization, table of random numbers. In this study, reading the table of predefined random numbers (for example, top or bottom) and the researcher's second default is to consider even numbers for group 1 and odd numbers for group 2. The researcher begins to read the numbers in a predetermined manner and the patients are divided into two groups, Blinding description: In this study, patients will be assigned to two groups. Patients are not relieved of the drug content they receive because the appearance of all medications is the same. Clinical caregivers who give medications to patients also did not know what medication to give. After the course of treatment, to assess the effectiveness of the medication, the assessor does not know which patient has been treated with what medication and only fills in the information related to the questionnaires. 3 Cataract. Intervention 1: Intervention group1: Receiver of ketorolac. Calm retention will be the same in all patients with midazolam 0.04 kg / mg and fentanyl 1.5 mg / kg. In this group, 2 drops of ketorolac are instilled into the eyes of patients every 6 hours. After 5 minutes, 0.5% tetracycline drops are instilled in both groups, then the eyes are swollen and puffy, and the surgeon will cover the field with phycoamulsification surgery. The patient's operation is transferred to recovery. The patient's eye complaints such as burning, itchy eyes, pain and severity of pain (according to VAS criteria) every 15 minutes in the recovery unit and in the ward every half hour until discharge from the hospital and the patient's satisfaction based on Likert criteria before discharge from the hospital. The study is evaluated and registered by an uninformed witness. Intervention 2: Intervention group2: Naphazoline-antazoline drug recipient. Calm retention will be the same in all patients with midazolam 0.04 kg / mg and fentanyl 1.5 mg / kg. In this group, 2 drops of Naphazoline-antazolin are instilled into the eyes of patients every 6 hours. After 5 minutes, 0.5% tetracycline drops are instilled in both groups, then the eyes are swollen and puffy, and the surgeon will cover the field with phycoamulsification surgery. The patient's operation is transferred to recovery. The patient's eye complaints such as burning, itchy eyes, pain and severity of pain (according to VAS criteria) every 15 minutes in the recovery unit and in the ward every half hour until discharge from the hospital and the patient's satisfaction based on Likert criteria before discharge from the hospital. The study is evaluated and registered by an uninformed witness. Yes - There is a plan to make this available What will be shared: All potential data can be shared after people have not been identified When: From 2021 To whom: Researchers working in academic and scientific institutions Conditions: Free and on Web Individuals can use the documents by visiting the research sites and the website of Isfahan University of Medical Sciences Where to obtain: Free and on Web. Individuals can use the documents by visiting the website of Isfahan University of Medical Sciences and submitting an application How to obtain: Free and on Web Comments:
public Hamidreza Shetai
Feyz hospial, Feyz Ave,. Isfahan
Isfahan Iran (Islamic Republic of) 8174673118 +98 31 3668 0048 hamidshetabi@med.mui.ac.ir Esfahan University of Medical Sciences scientific Hamidreza Shetai
Feyz hospial, Feyz Ave,. Isfahan
Isfahan Iran (Islamic Republic of) 8174673118 +98 31 3668 0048 hamidshetabi@med.mui.ac.ir Esfahan University of Medical Sciences Iran (Islamic Republic of) All of the Patients undergoing Phacoamulsification Surgery under sedation 18 years no limit Both Patients with glaucoma, uncontrolled hypertension, kidney disease, allergies to sedatives or studied Proven psycho-anxiety disorders Inability to follow up patients up to 0.5 hours after recovery History of allergy or allergic reaction to Sedatives or studies Any sensitivity to ketorolac H25 Age-related cataract Treatment - Drugs Treatment - Drugs Intervention group1: Receiver of ketorolac. Calm retention will be the same in all patients with midazolam 0.04 kg / mg and fentanyl 1.5 mg / kg. In this group, 2 drops of ketorolac are instilled into the eyes of patients every 6 hours. After 5 minutes, 0.5% tetracycline drops are instilled in both groups, then the eyes are swollen and puffy, and the surgeon will cover the field with phycoamulsification surgery. The patient's operation is transferred to recovery. The patient's eye complaints such as burning, itchy eyes, pain and severity of pain (according to VAS criteria) every 15 minutes in the recovery unit and in the ward every half hour until discharge from the hospital and the patient's satisfaction based on Likert criteria before discharge from the hospital. The study is evaluated and registered by an uninformed witness Intervention group2: Naphazoline-antazoline drug recipient. Calm retention will be the same in all patients with midazolam 0.04 kg / mg and fentanyl 1.5 mg / kg. In this group, 2 drops of Naphazoline-antazolin are instilled into the eyes of patients every 6 hours. After 5 minutes, 0.5% tetracycline drops are instilled in both groups, then the eyes are swollen and puffy, and the surgeon will cover the field with phycoamulsification surgery. The patient's operation is transferred to recovery. The patient's eye complaints such as burning, itchy eyes, pain and severity of pain (according to VAS criteria) every 15 minutes in the recovery unit and in the ward every half hour until discharge from the hospital and the patient's satisfaction based on Likert criteria before discharge from the hospital. The study is evaluated and registered by an uninformed witness Ocular Complaints. Timepoint: Every 15 minutes in the recovery unit and in the ward for half an hour until discharge from the hospital. Method of measurement: Questionnaire. Esfahan University of Medical Sciences Approved 2020-06-01 Ethics committee of IsfahanUniversity of Medical Sciences Isfahan University of Medical Sciences, Hezar Jarib Ave., Isfahan Isfahan Isfehan Iran (Islamic Republic of)